Products 1257044-40-8

CAS 1257044-40-8 appears in our catalog under these names: Venetoclax, ABT 199 (>99%)(Venetoclax), >95% (HPLC), ABT 199 (Venetoclax), >95% (HPLC), ABT–199, Venetoclax/ 99.96% (existing batch purity). Offered by: Chemat Brand, TRC, GLPBio, TargetMol, Biosynth. Available pack sizes: on request, 100mg, 10mg, 500mg, 50mg, 5mg, 1g, 10mM (in 1ml dmso).

Venetoclax
Chemat Brand, Biosynth
  • size: on request, 250mg, 100mg, 500mg
  • Variants: 6
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ABT 199 (>99%)(Venetoclax), >95% (HPLC)
TRC
  • size: 100mg, 10mg, 500mg
  • Variants: 3
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ABT 199 (Venetoclax), >95% (HPLC)
TRC
  • size: 100mg, 50mg, 5mg
  • Variants: 3
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ABT–199
GLPBio
  • size: 10mg, 100mg, 1g, 5mg
  • Variants: 7
from 611.08
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Venetoclax/ 99.96% (existing batch purity)
TargetMol
  • size: 1g, 5mg, 10mg, 50mg
  • Variants: 6
from 499.07
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Venetoclax, 95%
Thermo Scientific (Acros)
  • size: 100MG
  • Variants: 1
from 610.26
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4-[4-[[2-(4-Chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[3-nitro-4-[[(tetrahydro-2H-pyran-4-yl)methyl]amino]phenyl]sulfonyl]-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)-benzamide, 99%, 99%
Chemat
  • size: 5mg, 10mg, 100mg, 250mg
  • Variants: 10
from 78.80
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Venetoclax, 99.96%
MedChemExpress
  • size: 10 mg, 5 mg, 1 g, 50 mg
  • Variants: 8
from 407.93
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Venetoclax (Standard), 99.90%
MedChemExpress
  • size: 100 mg, 50 mg, 10 mg, 5 mg
  • Variants: 5
from 839.82
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Venetoclax, min. 95 %, 100 mg
Roth
  • size: 100mg
  • Variants: 1
from 1175.18
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Venetoclax, min. 95 %, 250 mg
Roth
  • size: 250mg
  • Variants: 1
from 2100.23
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Venetoclax, min. 95 %, 500 mg
Roth
  • size: 500mg
  • Variants: 1
from 3251.81
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Venetoclax is a member of the class of pyrrolopyridines that is a potent inhibitor of the antiapoptotic protein B-cell lymphoma 2. It is used for treamtment of chronic lymphocytic leukemia with 17p deletion. It has a role as a B-cell lymphoma 2 inhibitor, an antineoplastic agent and an apoptosis inducer. It is an aromatic ether, a C-nitro compound, a pyrrolopyridine, a N-alkylpiperazine, a N-arylpiperazine, a member of oxanes, a member of monochlorobenzenes and a N-sulfonylcarboxamide.

Source: ChEBI

Identity
Molecular formulaC45H50ClN7O7S
Molecular weight868.4 g/mol
IUPAC name4-[4-[[2-(4-chlorophenyl)-4,4-dimethylcyclohexen-1-yl]methyl]piperazin-1-yl]-N-[3-nitro-4-(oxan-4-ylmethylamino)phenyl]sulfonyl-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzamide
InChIKeyLQBVNQSMGBZMKD-UHFFFAOYSA-N
SMILESCC1(CCC(=C(C1)C2=CC=C(C=C2)Cl)CN3CCN(CC3)C4=CC(=C(C=C4)C(=O)NS(=O)(=O)C5=CC(=C(C=C5)NCC6CCOCC6)[N+](=O)[O-])OC7=CN=C8C(=C7)C=CN8)C

Computed by PubChem (NCBI)

Synonyms: Venetoclax, Venclexta, venclyxto, venetoclaxum, Venetoclax (ABT-199), Venetoclax (ABT199), C45H50ClN7O7S, Venetoclax; Abt-199, Venetoclax [USAN:INN], Venclexta (TN)
Related forms of this compound
4-[4-[[2-(4-chlorophenyl)-4,4-dimethylcyclohexen-1-yl]methyl]-2,2,3,3,5,5,6,6-octadeuteriopiperazin-1-yl]-N-[3-nitro-4-(oxan-4-ylmethylamino)phenyl]sulfonyl-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzamide C45H50ClN7O7S