Products 1281683-44-0

CAS 1281683-44-0 appears in our catalog under these names: dCeMM4, dCeMM4, 98.01%, dCeMM4, 98%, 3-(5-Methylfuran-2-carbonyl)-N-(5-methylthiazol-2-yl)thiazolidine-4-carboxamide, 98%. Offered by: GLPBio, MedChemExpress, Ambeed, BLDpharm, Fluorochem. Available pack sizes: 10mg, 100mg, 25mg, 5mg, 50mg, 5 mg, 100 mg, 25 mg.

dCeMM4
GLPBio, Chemat
  • size: 10mg, 100mg, 25mg, 5mg
  • Variants: 10
from 395.60
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dCeMM4, 98.01%
MedChemExpress
  • size: 5 mg, 100 mg, 25 mg, 10 mg
  • Variants: 5
from 839.82
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dCeMM4, 98%
Ambeed, Fluorochem
  • size: 250mg, 25mg, 50mg
  • Variants: 3
from 2272.75
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3-(5-Methylfuran-2-carbonyl)-N-(5-methylthiazol-2-yl)thiazolidine-4-carboxamide, 98%
BLDpharm
  • size: 25mg, 50mg, 100mg, 250mg
  • Variants: 4
from 547.61
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Structural formula: {0} (CAS {1})

DCeMM4 is a furan that is substituted by {4-[(5-methyl-1,3-thiazol-2-yl)carbamoyl]-1,3-thiazolidin-3-yl}carbonyl and methyl groups at positions 2 and 5, respectively. It is a glue degrader that induces the ubiquitination and degradation of cyclin K by prompting an interaction between CDK12:cyclin K with a CRL4B ligase complex. It is a secondary carboxamide, a tertiary carboxamide, a member of furans, a member of thiazolidines and a member of 1,3-thiazoles.

Source: ChEBI

Identity
Molecular formulaC14H15N3O3S2
Molecular weight337.4 g/mol
IUPAC name3-(5-methylfuran-2-carbonyl)-N-(5-methyl-1,3-thiazol-2-yl)-1,3-thiazolidine-4-carboxamide
InChIKeyBPWZJVKIVHVVHP-UHFFFAOYSA-N
SMILESCC1=CC=C(O1)C(=O)N2CSCC2C(=O)NC3=NC=C(S3)C

Computed by PubChem (NCBI)

Synonyms: dCeMM4, 3-(5-Methylfuran-2-carbonyl)-N-(5-methylthiazol-2-yl)thiazolidine-4-carboxamide, orb3177694