Products 128312-51-6

CAS 128312-51-6 appears in our catalog under these names: Cinalukast, Ro 24-5913. Offered by: TRC, GLPBio, Sigma-Aldrich, Chemat, MedChemExpress. Available pack sizes: 500mg, 10mg, 50mg, 5MG, Get quote.

Cinalukast
TRC, GLPBio, Sigma-Aldrich
  • size: 500mg, 10mg, 50mg, 5MG
  • Variants: 5
from 747.00
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Ro 24-5913
MedChemExpress
  • size: Get quote
  • Variants: 1
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Structural formula: {0} (CAS {1})

Cinalukast is 2,2-Diethylsuccinanilic acid substituted at a meta- position by an (E)-2-(4-cyclobutyl-1,3-thiazol-2-yl)ethenyl group. It selectively antagonizes leukotriene D4 at the cysteinyl leukotriene receptor, in the human airway, preventing airway edema, smooth muscle contraction, and enhanced secretion of thick, viscous mucus. It is used in the treatment of asthma. It has a role as an anti-arrhythmia drug, a leukotriene antagonist and an anti-asthmatic drug. It is a carboxylic acid and a member of 1,3-thiazoles.

Source: ChEBI

Identity
Molecular formulaC23H28N2O3S
Molecular weight412.5 g/mol
IUPAC name4-[3-[(E)-2-(4-cyclobutyl-1,3-thiazol-2-yl)ethenyl]anilino]-2,2-diethyl-4-oxobutanoic acid
InChIKeyBZMKNPGKXJAIDV-VAWYXSNFSA-N
SMILESCCC(CC)(CC(=O)NC1=CC=CC(=C1)/C=C/C2=NC(=CS2)C3CCC3)C(=O)O

Computed by PubChem (NCBI)

Synonyms: Cinalukast, Ro 24-5913, Ro-24-5913, 3'-((E)-2-(4-Cyclobutyl-2-thiazolyl)vinyl)-2,2-diethylsuccinanilic acid, Ro-245913, cinalukastum, Cinalukast [USAN:INN], Cinalukast (USAN/INN), CINALUKAST [INN], CINALUKAST [USAN]