Products 129-46-4
CAS 129-46-4 appears in our catalog under these names: Suramin (Sodium Salt), >95% (HPLC), Suramin Sodium Salt/ 99.76% (existing batch purity), Suramin hexasodium salt, Suramin hexasodium salt, 98+% , Suramin hexasodium salt hydrate. Offered by: TRC, TargetMol, GLPBio, Thermo Scientific (Alfa Aesar), Biosynth. Available pack sizes: 500mg, 50mg, 5mg, 1mg, 10mg, 25mg, 100mg, 10mM (in 1ml dmso).
Suramin sodium is an organic sodium salt that is the hexasodium salt of suramin. It is an FDA approved drug for African sleeping sickness and river blindness. It has a role as an antinematodal drug, an antineoplastic agent, a trypanocidal drug, an EC 2.7.11.13 (protein kinase C) inhibitor, a GABA-gated chloride channel antagonist, an angiogenesis inhibitor, a GABA antagonist, a ryanodine receptor agonist, an apoptosis inhibitor and a purinergic receptor P2 antagonist. It contains a suramin(6-).
Source: ChEBI
| Molecular formula | C51H34N6Na6O23S6 |
|---|---|
| Molecular weight | 1429.2 g/mol |
| IUPAC name | hexasodium;8-[[4-methyl-3-[[3-[[3-[[2-methyl-5-[(4,6,8-trisulfonatonaphthalen-1-yl)carbamoyl]phenyl]carbamoyl]phenyl]carbamoylamino]benzoyl]amino]benzoyl]amino]naphthalene-1,3,5-trisulfonate |
| InChIKey | VAPNKLKDKUDFHK-UHFFFAOYSA-H |
| SMILES | CC1=C(C=C(C=C1)C(=O)NC2=C3C(=CC(=CC3=C(C=C2)S(=O)(=O)[O-])S(=O)(=O)[O-])S(=O)(=O)[O-])NC(=O)C4=CC(=CC=C4)NC(=O)NC5=CC=CC(=C5)C(=O)NC6=C(C=CC(=C6)C(=O)NC7=C8C(=CC(=CC8=C(C=C7)S(=O)(=O)[O-])S(=O)(=O)[O-])S(=O)(=O)[O-])C.[Na+].[Na+].[Na+].[Na+].[Na+].[Na+] |
Computed by PubChem (NCBI)
Synonyms:
SURAMIN SODIUM, Suramin hexasodium, Antrypol, Moranyl, Suramine sodique, Nagananinum, Naganine, Naganinum, Germanin, Naganin