Products 130726-68-0

CAS 130726-68-0 appears in our catalog under these names: Neticonazole, Neticonazole/ 99.58% (existing batch purity), Neticonazole, 98%, 98%, Neticonazole, 99.88%, Neticonazole (Standard). Offered by: Chemat Brand, TargetMol, GLPBio, Biosynth, Chemat. Available pack sizes: on request, 5mg, 100mg, 25mg, 10mM (in 1ml dmso), 50mg, 250mg, 500mg.

Neticonazole
Chemat Brand, GLPBio, Biosynth
  • size: on request, 100mg, 25mg, 10mM (in 1ml dmso)
  • Variants: 7
from 732.77
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Neticonazole/ 99.58% (existing batch purity)
TargetMol
  • size: 5mg
  • Variants: 1
from 405.71
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Neticonazole, 98%, 98%
Chemat
  • size: 25mg, 50mg, 100mg, 250mg
  • Variants: 4
from 486.80
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Neticonazole, 99.88%
MedChemExpress
  • size: 50 mg, 100 mg, 25 mg, 10mM/1mL
  • Variants: 4
from 519.38
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Neticonazole (Standard)
MedChemExpress
  • size: 5 mg, 50 mg, 25 mg, 100 mg
  • Variants: 5
from 468.30
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Structural formula: {0} (CAS {1})

Neticonazole is an enamine that is ethene which is substituted at positions 1, 1, and 2 by o-pentoxyphenyl, 1H-imidazol-1-yl, and methylthio groups, respectively (the E isomer). An inhibitor of P450-dependent C-14alpha-demethylation of lanosterol (preventing conversion to ergosterol and inhibiting cell wall synthesis in fungi), it is used in Japan (generally as the corresponding hydrochloride salt) as an antifungal drug for the treatment of superficial skin infections. It has a role as an EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor and an antifungal drug. It is a member of benzenes, a member of imidazoles, an aromatic ether, an enamine, a methyl sulfide, an imidazole antifungal drug and a conazole antifungal drug. It is a conjugate base of a neticonazole(1+).

Source: ChEBI

Identity
Molecular formulaC17H22N2OS
Molecular weight302.4 g/mol
IUPAC name1-[(E)-2-methylsulfanyl-1-(2-pentoxyphenyl)ethenyl]imidazole
InChIKeyVWOIKFDZQQLJBJ-DTQAZKPQSA-N
SMILESCCCCCOC1=CC=CC=C1/C(=C\SC)/N2C=CN=C2

Computed by PubChem (NCBI)

Synonyms: Neticonazole, Neticonazol, Neticonazolum, Atolant, Neticonazole [INN], 1-[(E)-2-methylsulfanyl-1-(2-pentoxyphenyl)ethenyl]imidazole, (E)-1-(2-(Methylthio)-1-(2-(pentyloxy)phenyl)vinyl)-1H-imidazole, (E)-1-(2-(Methylthio)-1-(o-(pentyloxy)phenyl)vinyl)imidazole, Neticonazolum [INN-Latin], Neticonazol [INN-Spanish]