Products 1350462-55-3

CAS 1350462-55-3 appears in our catalog under these names: MK–5172 hydrate, Grazoprevir hydrate, Grazoprevir hydrate, 99.99%, Grazoprevir hydrate, 99+%, (33R,35S,91R,92R,5S)-5-(tert-Butyl)-N-((1R,2S)-1-((cyclopropylsulfonyl)carbamoyl)-2-vinylcyclopropyl)-17-methoxy-4,7-dioxo-2,8-dioxa-6-aza-1(2,3)-quinoxalina-3(3,1)-pyrrolidina-9(1,2)-cyclopropanacyclotetradecaphane-35-carboxamide hydrate, 99+%. Offered by: GLPBio, Biosynth, MedChemExpress, Ambeed, BLDpharm. Available pack sizes: 10mg, 100mg, 5mg, 50mg, 25mg, 5 mg, 50 mg, 25 mg.

MK–5172 hydrate
GLPBio
  • size: 10mg, 100mg, 5mg, 50mg
  • Variants: 4
from 709.37
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Grazoprevir hydrate
Biosynth
  • size: 25mg, 50mg, 100mg
  • Variants: 3
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Grazoprevir hydrate, 99.99%
MedChemExpress
  • size: 5 mg, 50 mg, 25 mg, 100 mg
  • Variants: 6
from 640.13
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Grazoprevir hydrate, 99+%
Ambeed
  • size: 250mg
  • Variants: 1
from 1816.62
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(33R,35S,91R,92R,5S)-5-(tert-Butyl)-N-((1R,2S)-1-((cyclopropylsulfonyl)carbamoyl)-2-vinylcyclopropyl)-17-methoxy-4,7-dioxo-2,8-dioxa-6-aza-1(2,3)-quinoxalina-3(3,1)-pyrrolidina-9(1,2)-cyclopropanacyclotetradecaphane-35-carboxamide hydrate, 99+%
BLDpharm
  • size: 50mg, 100mg, 250mg
  • Variants: 3
from 603.15
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Cyclopropanecarboxamide, N-[[[(1R,2R)-2-[5-(3-hydroxy-6-methoxy-2-quinoxalinyl)pentyl]cyclopropyl]oxy]carbonyl]-3-methyl-L-valyl-(4R)-4-hydroxy-L-prolyl-1-amino-N-(cyclopropylsulfonyl)-2-ethenyl-, cyclic (1→2)-ether, hydrate (1:1), (1R,2S)-, 99+%
Chemat
  • size: 10mg, 50mg, 100mg, 250mg
  • Variants: 4
from 496.40
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Structural formula: {0} (CAS {1})

Grazoprevir is an azamacrocyclic compound that is a hepatitis C protease inhibitor used in combination with elbasvir (under the brand name Zepatier) for treatment of chronic HCV genotypes 1 or 4 infection in adults. It has a role as an antiviral drug, a hepatoprotective agent and a hepatitis C protease inhibitor. It is a carbamate ester, a lactam, an aromatic ether, a quinoxaline derivative, a member of cyclopropanes, an azamacrocycle and a N-sulfonylcarboxamide.

Source: ChEBI

Identity
Molecular formulaC38H50N6O9S
Molecular weight766.9 g/mol
IUPAC name(1R,18R,20R,24S,27S)-24-tert-butyl-N-[(1R,2S)-1-(cyclopropylsulfonylcarbamoyl)-2-ethenylcyclopropyl]-7-methoxy-22,25-dioxo-2,21-dioxa-4,11,23,26-tetrazapentacyclo[24.2.1.03,12.05,10.018,20]nonacosa-3,5(10),6,8,11-pentaene-27-carboxamide
InChIKeyOBMNJSNZOWALQB-NCQNOWPTSA-N
SMILESCC(C)(C)[C@H]1C(=O)N2C[C@@H](C[C@H]2C(=O)N[C@@]3(C[C@H]3C=C)C(=O)NS(=O)(=O)C4CC4)OC5=NC6=C(C=CC(=C6)OC)N=C5CCCCC[C@@H]7C[C@H]7OC(=O)N1

Computed by PubChem (NCBI)

Synonyms: Grazoprevir, grazoprevirum, Grazoprevir Hydrate, Grazoprevir monohydrate, Grazoprevir anhydrous, Grazoprevir [INN], GRAZOPREVIR [MI], Grazoprevir (USAN/INN), GRAZOPREVIR [WHO-DD], orb1223339
Related forms of this compound
(1R,18R,20R,24S,27S)-24-tert-butyl-N-[(1R,2S)-1-(cyclopropylsulfonylcarbamoyl)-2-ethenylcyclopropyl]-7-methoxy-22,25-dioxo-2,21-dioxa-4,11,23,26-tetrazapentacyclo[24.2.1.03,12.05,10.018,20]nonacosa-3,5(10),6,8,11-pentaene-27-carboxamide C38H50N6O9S