Products 1350653-20-1

CAS 1350653-20-1 appears in our catalog under these names: Methyl (4,6-diamino-2-(5-fluoro-1-(2-fluorobenzyl)-1h-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-5-yl)carbamate, 95%, Vericiguat, Vericiguat/ 99.71% (existing batch purity), Vericiguat (BAY1021189), Vericiguat 99%. Offered by: Combi-blocks, Chemat Brand, TRC, TargetMol, GLPBio. Available pack sizes: 500mg, 100mg, on request, 50mg, 1mg, 5mg, 10mg, 25mg.

Methyl (4,6-diamino-2-(5-fluoro-1-(2-fluorobenzyl)-1h-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-5-yl)carbamate, 95%
Combi-blocks
  • size: 500mg, 100mg
  • Variants: 2
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Vericiguat
Chemat Brand, TRC
  • size: on request, 50mg
  • Variants: 2
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Vericiguat/ 99.71% (existing batch purity)
TargetMol
  • size: 1mg, 5mg, 10mg, 25mg
  • Variants: 6
from 452.11
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Vericiguat (BAY1021189)
GLPBio
  • size: 10mg, 100mg, 10mM (in 1ml dmso), 2mg
  • Variants: 6
from 840.43
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Vericiguat 99%
Ambeed
  • size: 50mg, 100mg, 250mg, 1g
  • Variants: 7
from 331.44
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Vericiguat, 99.27%
MedChemExpress
  • size: 2 mg, 5 mg, 10 mg, 50 mg
  • Variants: 6
from 454.37
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Vericiguat (Standard), 98.87%
MedChemExpress
  • size: 50 mg, 100 mg, 25 mg, 10 mg
  • Variants: 5
from 1369.24
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Methyl N-[4,6-diamino-2-[5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-yl]carbamate, 99%, 99%
Chemat
  • size: 50mg, 100mg, 250mg, 1g
  • Variants: 6
from 136.40
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VERICIGUAT, 99%
Fluorochem
  • size: 50mg, 100mg, 250mg, 1g
  • Variants: 4
from 206.20
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Structural formula: {0} (CAS {1})

Vericiguat is a pyrazolopyridine that is 5-fluoro-1H-pyrazolo[3,4-b]pyridine in which the amino hydrogen at position 1 has been substituted by a 2-fluorobenzyl group and the hydrogen at position 3 has been substituted by a 4,6-diamino-5-[(methoxycarbonyl)amino]pyrimidin-2-yl group. It is a soluble guanylate cyclase stimulator which is used for treatment of chronic heart failure. It has a role as a vasodilator agent, an antihypertensive agent and a soluble guanylate cyclase activator. It is a carbamate ester, an organofluorine compound, an aminopyrimidine and a pyrazolopyridine.

Source: ChEBI

Identity
Molecular formulaC19H16F2N8O2
Molecular weight426.4 g/mol
IUPAC namemethyl N-[4,6-diamino-2-[5-fluoro-1-[(2-fluorophenyl)methyl]pyrazolo[5,4-b]pyridin-3-yl]pyrimidin-5-yl]carbamate
InChIKeyQZFHIXARHDBPBY-UHFFFAOYSA-N
SMILESCOC(=O)NC1=C(N=C(N=C1N)C2=NN(C3=C2C=C(C=N3)F)CC4=CC=CC=C4F)N

Computed by PubChem (NCBI)

Synonyms: Vericiguat, Verquvo, vericiguatum, Vericiguat [INN], Vericiguat [USAN], VERICIGUAT [JAN], Veicigguat, Verquvo (TN), Vericiguat (Standard), Vericiguat [USAN:INN]