Products 1354690-24-6

CAS 1354690-24-6 appears in our catalog under these names: Leniolisib, Leniolisib, 99.38%, Leniolisib, 99%, (S)-1-(3-((6-(6-Methoxy-5-(trifluoromethyl)pyridin-3-yl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-yl)amino)pyrrolidin-1-yl)propan-1-one, 99%. Offered by: GLPBio, Biosynth, MedChemExpress, Fluorochem, Ambeed. Available pack sizes: 1mg, 10mg, 5mg, 10mM (in 1ml dmso), 50mg, 25mg, 100mg, 25 mg.

Leniolisib
GLPBio, Biosynth
  • size: 1mg, 10mg, 5mg, 10mM (in 1ml dmso)
  • Variants: 9
from 620.44
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Leniolisib, 99.38%
MedChemExpress
  • size: 25 mg, 50 mg, 10 mg, 10mM/1mL
  • Variants: 7
from 551.89
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Leniolisib, 99%
Fluorochem, Ambeed
  • size: 1mg, 5mg, 10mg, 25mg
  • Variants: 8
from 232.23
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(S)-1-(3-((6-(6-Methoxy-5-(trifluoromethyl)pyridin-3-yl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-yl)amino)pyrrolidin-1-yl)propan-1-one, 99%
Chemat, BLDpharm
  • size: 1mg, 5mg, 10mg, 25mg
  • Variants: 11
from 165.20
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Structural formula: {0} (CAS {1})

Leniolisib is a pyridopyrimidine that is 5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine substituted by [(3S)-1-propanoylpyrrolidin-3-yl]amino and 6-methoxy-5-(trifluoromethyl)pyridin-3-yl groups at positions 4 and 6, respectively. It has a role as an EC 2.7.1.153 (phosphatidylinositol-4,5-bisphosphate 3-kinase) inhibitor and an immunomodulator. It is a tertiary carboxamide, a member of pyridines, an aromatic ether, an organofluorine compound, a member of pyrrolidines, a pyridopyrimidine and a secondary amino compound.

Source: ChEBI

Identity
Molecular formulaC21H25F3N6O2
Molecular weight450.5 g/mol
IUPAC name1-[(3S)-3-[[6-[6-methoxy-5-(trifluoromethyl)-3-pyridinyl]-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-4-yl]amino]pyrrolidin-1-yl]propan-1-one
InChIKeyMWKYMZXCGYXLPL-ZDUSSCGKSA-N
SMILESCCC(=O)N1CC[C@@H](C1)NC2=NC=NC3=C2CN(CC3)C4=CC(=C(N=C4)OC)C(F)(F)F

Computed by PubChem (NCBI)

Synonyms: Leniolisib, Cdz173 free base, Cdz-173 free base, leniolisibum, Leniolisib [INN], Leniolisib free base, leniolisib (CDZ 173), Leniolisib (CDZ173), Leniolisib; CDZ173, Leniolisib (USAN/INN)