Products 136817-59-9

CAS 136817-59-9 appears in our catalog under these names: Delavirdine, Delavirdine 99%, N-[2-(4-{3-[(propan-2-yl)amino]pyridin-2-yl}piperazine-1-carbonyl)-1H-indol-5-yl]methanesulfonamide, 99%, 99%, Delavirdine, 99.70%, Delavirdine (Standard). Offered by: TRC, Ambeed, Chemat, MedChemExpress. Available pack sizes: 10mg, 25mg, 5mg, 50mg, 100mg, 250mg, 1g, 10 mg.

Delavirdine
TRC
  • size: 10mg, 25mg, 5mg
  • Variants: 3
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Delavirdine 99%
Ambeed
  • size: 5mg, 10mg, 25mg, 50mg
  • Variants: 7
from 225.75
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N-[2-(4-{3-[(propan-2-yl)amino]pyridin-2-yl}piperazine-1-carbonyl)-1H-indol-5-yl]methanesulfonamide, 99%, 99%
Chemat
  • size: 10mg, 250mg, 100mg
  • Variants: 3
from 256.40
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Delavirdine, 99.70%
MedChemExpress
  • size: 10 mg, 5 mg, 200 mg, 10mM/1mL
  • Variants: 6
from 315.05
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Delavirdine (Standard)
MedChemExpress
  • size: 25 mg, 10 mg, 100 mg, 5 mg
  • Variants: 5
from 598.33
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Structural formula: {0} (CAS {1})

Delavirdine is the amide resulting from the formal condensation of 5-[(methylsulfonyl)amino]-1H-indole-2-carboxylic acid and 4-amino group of 1-[3-(isopropylamino)pyridin-2-yl]piperazine, delavirdine is a non-nucleoside reverse transcriptase inhibitor with activity specific for HIV-1. Viral resistance emerges rapidly when delavirdine is used alone, so it is therefore used (as the methanesulfonic acid salt) with other antiretrovirals for combination therapy of HIV infection. It has a role as an antiviral drug and a HIV-1 reverse transcriptase inhibitor. It is a sulfonamide, an aminopyridine, a N-acylpiperazine and an indolecarboxamide.

Source: ChEBI

Identity
Molecular formulaC22H28N6O3S
Molecular weight456.6 g/mol
IUPAC nameN-[2-[4-[3-(propan-2-ylamino)-2-pyridinyl]piperazine-1-carbonyl]-1H-indol-5-yl]methanesulfonamide
InChIKeyWHBIGIKBNXZKFE-UHFFFAOYSA-N
SMILESCC(C)NC1=C(N=CC=C1)N2CCN(CC2)C(=O)C3=CC4=C(N3)C=CC(=C4)NS(=O)(=O)C

Computed by PubChem (NCBI)

Synonyms: Delavirdine, Delavirdina, Delavirdinum, Delavirdine [INN], u-90152, Delavirdine (INN), DLV, DELAVIRDINE [MI], Rescriptor (TM), Delavirdine (*Mesylate salt*)