Products 1377049-84-7

CAS 1377049-84-7 appears in our catalog under these names: Velpatasvir, Velpatasvir, >95% (HPLC), Velpatasvir R Isomer (Imidazole), Velpatasvir/ 99.91% (existing batch purity), Methyl [(2S)-1-[(2S,5S)-2-[9-[2-[(2S,4S)-1-[(2R)-2-[(methoxycarbonyl)amino]-2-phenylacetyl]-4-(methoxymethyl)pyrrolidin-2-yl]-1H-imidazol-5-yl]-1,11-dihydroisochromeno[4',3':6,7]naphtho[1,2-d]imidazol-2-yl]-5-methylpyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]carbamate, 99%, 99%. Offered by: Chemat Brand, Hubei YoungXin, TRC, TargetMol, GLPBio. Available pack sizes: on request, 10mg, 25mg, 50mg, 100mg, 200mg, 5mg, 500mg.

Velpatasvir
Chemat Brand, Hubei YoungXin, GLPBio
  • size: on request, 10mg, 25mg, 50mg
  • Variants: 17
from 517.47
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Velpatasvir, >95% (HPLC)
TRC
  • size: 100mg, 25mg, 50mg
  • Variants: 3
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Velpatasvir R Isomer (Imidazole)
TRC
  • size: 25mg
  • Variants: 1
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Velpatasvir/ 99.91% (existing batch purity)
TargetMol
  • size: 5mg, 10mg, 25mg, 50mg
  • Variants: 7
from 386.15
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Methyl [(2S)-1-[(2S,5S)-2-[9-[2-[(2S,4S)-1-[(2R)-2-[(methoxycarbonyl)amino]-2-phenylacetyl]-4-(methoxymethyl)pyrrolidin-2-yl]-1H-imidazol-5-yl]-1,11-dihydroisochromeno[4',3':6,7]naphtho[1,2-d]imidazol-2-yl]-5-methylpyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]carbamate, 99%, 99%
Chemat
  • size: 250mg, 1g, 5g, 1mg
  • Variants: 6
from 78.80
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Velpatasvir, 99.83%
MedChemExpress
  • size: 100 mg, 5 mg, 10mM/1mL, 10 mg
  • Variants: 5
from 301.12
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Velpatasvir (Standard), 99.68%
MedChemExpress
  • size: 25 mg, 50 mg, 10 mg, 5 mg
  • Variants: 5
from 575.11
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Velpatasvir, 25 mg
Roth
  • size: 25mg
  • Variants: 1
from 892.01
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Velpatasvir, 50 mg
Roth
  • size: 50mg
  • Variants: 1
from 1411.16
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Velpatasvir, 100 mg
Roth
  • size: 100mg
  • Variants: 1
from 1911.44
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Velpatasvir, 250 mg
Roth
  • size: 250mg
  • Variants: 1
from 2666.58
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Velpatasvir-13C2-d6
Chemat Brand
  • size: on request
  • Variants: 1
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Velpatasvir-13C2-d6
Hubei YoungXin
  • size: 10mg, 25mg, 50mg, 100mg
  • Variants: 5
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Structural formula: {0} (CAS {1})

Velpatasvir is a complex organic heteropentacyclic compound that is a hepatitis C virus nonstructural protein 5A inhibitor used in combination with sofosbuvir (under the brand name Epclusa) for treatment of patients with chronic hepatitis C of all six major genotypes. It has a role as an antiviral drug and a hepatitis C virus nonstructural protein 5A inhibitor. It is a carbamate ester, a member of imidazoles, an ether, a ring assembly, an organic heteropentacyclic compound, a N-acylpyrrolidine and a L-valine derivative.

Source: ChEBI

Identity
Molecular formulaC49H54N8O8
Molecular weight883.0 g/mol
IUPAC namemethyl N-[(1R)-2-[(2S,4S)-2-[5-[6-[(2S,5S)-1-[(2S)-2-(methoxycarbonylamino)-3-methylbutanoyl]-5-methylpyrrolidin-2-yl]-21-oxa-5,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-1(13),2,4(8),5,9,11,14(19),15,17-nonaen-17-yl]-1H-imidazol-2-yl]-4-(methoxymethyl)pyrrolidin-1-yl]-2-oxo-1-phenylethyl]carbamate
InChIKeyFHCUMDQMBHQXKK-CDIODLITSA-N
SMILESC[C@H]1CC[C@H](N1C(=O)[C@H](C(C)C)NC(=O)OC)C2=NC3=C(N2)C=CC4=CC5=C(C=C43)OCC6=C5C=CC(=C6)C7=CN=C(N7)[C@@H]8C[C@@H](CN8C(=O)[C@@H](C9=CC=CC=C9)NC(=O)OC)COC

Computed by PubChem (NCBI)

Synonyms: Velpatasvir, EPCLUSA COMPONENT VELPATASVIR, velpatasvirum, Velpatasvir R Isomer (Imidazole), Velpatasvir [USAN:INN], Velpatasvir [INN], Velpatasvir (Standard), Velpatasvir(GS5816), VELPATASVIR [MI], VELPATASVIR [JAN]
Related forms of this compound
methyl N-[(1S)-2-[(2S,4S)-2-[5-[6-[(2S,5S)-1-[(2S)-2-(methoxycarbonylamino)-3-methylbutanoyl]-5-methylpyrrolidin-2-yl]-21-oxa-5,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-1(13),2,4(8),5,9,11,14(19),15,17-nonaen-17-yl]-1H-imidazol-2-yl]-4-(methoxymethyl)pyrrolidin-1-yl]-2-oxo-1-phenylethyl]carbamate C49H54N8O8
methyl N-[(1R)-2-[(2S,4S)-4-(methoxymethyl)-2-[5-[6-[(2S,5S)-5-methyl-1-[(2S)-2,3,4,4,4-pentadeuterio-2-(methoxycarbonylamino)-3-(trideuteriomethyl)butanoyl]pyrrolidin-2-yl]-21-oxa-5,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-1(13),2,4(8),5,9,11,14(19),15,17-nonaen-17-yl]-1H-imidazol-2-yl]pyrrolidin-1-yl]-2-oxo-1-phenylethyl]carbamate C49H54N8O8