Products 138605-00-2

CAS 138605-00-2 appears in our catalog under these names: NKH 477, NKH477, NKH 477, NKH477 (hydrochloride), NKH477, 99.86%. Offered by: TRC, TargetMol, GLPBio, Biosynth, Chemat. Available pack sizes: 250mg, 2mg, 1mg, 10mg, 5mg, 25mg, 10 mg, 100 mg.

NKH 477
TRC, Biosynth
  • size: 250mg, 5mg, 10mg, 25mg
  • Variants: 4
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NKH477
TargetMol
  • size: 2mg
  • Variants: 1
from 578.44
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NKH 477
GLPBio
  • size: 1mg, 10mg, 5mg
  • Variants: 3
from 536.19
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NKH477 (hydrochloride)
Chemat
  • size: 5mg
  • Variants: 1
from 688.40
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NKH477, 99.86%
MedChemExpress
  • size: 10 mg, 100 mg, 50 mg, 25 mg
  • Variants: 5
from 598.33
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Structural formula: {0} (CAS {1})

Colforsin daropate hydrochloride is the hydrochloride salt of colforsin daropate. It is a drug used for the treatment of acute heart failure. It directly stimulates adenylate cyclase and produces positive inotropic and vasodilator effects accompanied by the increase in cellular cAMP. It has a role as a vasodilator agent, an antihypertensive agent, a cardiotonic drug and an adenylate cyclase agonist. It contains a colforsin daropate(1+).

Source: ChEBI

Identity
Molecular formulaC27H44ClNO8
Molecular weight546.1 g/mol
IUPAC name[(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-acetyloxy-3-ethenyl-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-5,6,6a,8,9,10-hexahydro-2H-benzo[f]chromen-6-yl] 3-(dimethylamino)propanoate;hydrochloride
InChIKeyVIRRLEDAYYYTOD-YHEOSNBFSA-N
SMILESCC(=O)O[C@H]1[C@H]([C@@H]2[C@]([C@H](CCC2(C)C)O)([C@@]3([C@@]1(O[C@@](CC3=O)(C)C=C)C)O)C)OC(=O)CCN(C)C.Cl

Computed by PubChem (NCBI)

Synonyms: Adehl, Colforsin daropate hydrochloride, Colforsin dapropate hydrochloride, Colforsin dapropate HCl, 6-(3-Dimethylaminopropionyl)forskolin hydrochloride, colforsin daropate HCl, Colforsin daropate hydrochloride (JAN), Adehl (TN), Colforsin daropate hci, COLFORSIN DAROPATE HYDROCHLORIDE [JAN]