Products 1392275-56-7

CAS 1392275-56-7 appears in our catalog under these names: Tenofovir alafenamide hemifumarate/ 98.37% (existing batch purity), 1-Methylethyl N-((S)-(((1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy)methyl)phenoxyphosphinoyl)-L-alaninate, Tenofovir alafenamide hemifumarate, 99.92%, Tenofovir alafenamide hemifumarate (Standard), Tenofovir alafenamide hemifumarate, 99+%. Offered by: TargetMol, Biosynth, MedChemExpress, Ambeed, BLDpharm. Available pack sizes: 10mg, 25mg, 50mg, 100mg, 500mg, 1g, 2g, 5g.

Tenofovir alafenamide hemifumarate/ 98.37% (existing batch purity)
TargetMol
  • size: 10mg, 25mg, 50mg, 100mg
  • Variants: 5
from 405.71
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1-Methylethyl N-((S)-(((1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy)methyl)phenoxyphosphinoyl)-L-alaninate
Biosynth
  • size: 1g, 2g, 5g
  • Variants: 3
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Tenofovir alafenamide hemifumarate, 99.92%
MedChemExpress
  • size: 5 mg, 10 mg, 10mM/1mL, 100 mg
  • Variants: 5
from 361.49
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Tenofovir alafenamide hemifumarate (Standard)
MedChemExpress
  • size: 10 mg, 100 mg, 25 mg, 5 mg
  • Variants: 5
from 719.08
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Tenofovir alafenamide hemifumarate, 99+%
Ambeed
  • size: 100mg, 250mg, 1g, 5g
  • Variants: 5
from 209.06
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Isopropyl (((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-L-alaninate hemifumarate, 99+%
BLDpharm
  • size: 10mg, 50mg, 100mg, 250mg
  • Variants: 7
from 131.09
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L-Alanine, N-[(S)-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]phenoxyphosphinyl]-, 1-methylethyl ester, (2E)-2-butenedioate (2:1), 98%
Chemat
  • size: 100mg, 250mg, 1g, 5g
  • Variants: 5
from 122.00
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Structural formula: {0} (CAS {1})

Tenofovir alafenamide fumarate is a fumarate salt prepared from tenofovir alafenamide by reaction of one molecule of fumaric acid for every two molecules of tenofovir alafenamide. A prodrug for tenofovir, it is used in combination therapy for the treatment of HIV-1 infection. It has a role as an antiviral drug, a prodrug and a HIV-1 reverse transcriptase inhibitor. It contains a tenofovir alafenamide(1+).

Source: ChEBI

Identity
Molecular formulaC46H62N12O14P2
Molecular weight1069.0 g/mol
IUPAC name(E)-but-2-enedioic acid;bis(propan-2-yl (2S)-2-[[[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-phenoxyphosphoryl]amino]propanoate)
InChIKeySVUJNSGGPUCLQZ-FQQAACOVSA-N
SMILESC[C@H](CN1C=NC2=C(N=CN=C21)N)OC[P@@](=O)(N[C@@H](C)C(=O)OC(C)C)OC3=CC=CC=C3.C[C@H](CN1C=NC2=C(N=CN=C21)N)OC[P@@](=O)(N[C@@H](C)C(=O)OC(C)C)OC3=CC=CC=C3.C(=C/C(=O)O)\C(=O)O

Computed by PubChem (NCBI)

Synonyms: Tenofovir Alafenamide fumarate, tenofovir alafenamide hemifumarate, TAF, DESCOVY COMPONENT TENOFOVIR ALAFENAMIDE FUMARATE, ODEFSEY COMPONENT TENOFOVIR ALAFENAMIDE FUMARATE, SYMTUZA COMPONENT TENOFOVIR ALAFENAMIDE FUMARATE, BIKTARVY COMPONENT TENOFOVIR ALAFENAMIDE FUMARATE, TENOFOVIR ALAFENAMIDE FUMARATE COMPONENT OF ODEFSEY, TENOFOVIR ALAFENAMIDE FUMARATE COMPONENT OF BIKTARVY, TENOFOVIR ALAFENAMIDE FUMARATE COMPONENT OF DESCOVY