Products 140187-23-1

CAS 140187-23-1 appears in our catalog under these names: (S)-(-)-5-Fluorowillardiine, >95% (HPLC), (S)-(-)-5-Fluorowillardiine, 99+%, (S)-(-)-5-Fluorowillardiine/ 99.6% (existing batch purity), (S)–(–)–5–Fluorowillardiine, (αS)-α-Amino-5-fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinepropanoic acid, 98%, 98%. Offered by: TRC, AmBeed, TargetMol, GLPBio, Chemat. Available pack sizes: 10mg, 50mg, 1g, 250mg, 1mg, 2mg, 5mg, 25mg.

Structural formula: {0} (CAS {1})

3-(5-fluorouracil-1-yl)-L-alanine is an alanine derivative that is L-alanine bearing a 5-fluorouracil-1-yl substituent at position 3. A more potent and selective AMPA receptor agonist (at hGluR1 and hGluR2) than AMPA itself (Ki = 14.7, 25.1, and 1820 nM for hGluR1, hGluR2 and hGluR5 respectively). It has a role as an AMPA receptor agonist. It is an organofluorine compound, a non-proteinogenic L-alpha-amino acid and a L-alanine derivative. It is functionally related to a uracil.

Source: ChEBI

Identity
Molecular formulaC7H8FN3O4
Molecular weight217.15 g/mol
IUPAC name(2S)-2-amino-3-(5-fluoro-2,4-dioxopyrimidin-1-yl)propanoic acid
InChIKeyDBWPFHJYSTVBCZ-BYPYZUCNSA-N
SMILESC1=C(C(=O)NC(=O)N1C[C@@H](C(=O)O)N)F

Computed by PubChem (NCBI)