Products 1401966-69-5
CAS 1401966-69-5 appears in our catalog under these names: GSK2879552, GSK2879552, 98%, GSK2879552/ 99.22% (existing batch purity), 4-[[4-[[[(1R,2S)-2-Phenylcyclopropyl]amino]methyl]-1-piperidinyl]methyl]benzoic acid, 98%, 98%, GSK2879552, 99.98%. Offered by: GLPBio, AmBeed, TargetMol, Biosynth, Chemat. Available pack sizes: 5mg, 250mg, 1g, 100mg, 2mg, 25mg, 10mM (in 1ml dmso), 50mg.
GSK2879552 is a member of the class of piperidines that is piperidine substituted by (4-carboxyphenyl)methyl and {[(1R,2S)-2-phenylcyclopropyl]amino}methyl groups at positions 1 and 4, respectively. It is a potent and irreversible inhibitor of lysine specific demethylase 1 (LSD1, also known as KDM1A). It was under clinical investigation for the treatment of acute myeloid leukaemia and small cell lung carcinoma. It has a role as an EC 1.14.99.66 (lysine-specific histone demethylase 1A) inhibitor and an antineoplastic agent. It is a member of benzenes, a member of benzoic acids, a monocarboxylic acid, a member of piperidines, a secondary amino compound, a tertiary amino compound and a member of cyclopropanes.
Source: ChEBI
| Molecular formula | C23H28N2O2 |
|---|---|
| Molecular weight | 364.5 g/mol |
| IUPAC name | 4-[[4-[[[(1R,2S)-2-phenylcyclopropyl]amino]methyl]piperidin-1-yl]methyl]benzoic acid |
| InChIKey | LRULVYSBRWUVGR-FCHUYYIVSA-N |
| SMILES | C1CN(CCC1CN[C@@H]2C[C@H]2C3=CC=CC=C3)CC4=CC=C(C=C4)C(=O)O |
Computed by PubChem (NCBI)