Products 1404559-91-6
CAS 1404559-91-6 appears in our catalog under these names: BRD4884, BRD4884, 99.0%, BRD4884, 97%, N-(4-Amino-4'-fluoro-[1,1'-biphenyl]-3-yl)tetrahydro-2H-pyran-4-carboxamide, 97%. Offered by: TargetMol, GLPBio, MedChemExpress, Ambeed, BLDpharm. Available pack sizes: 5mg, 500ug, 1mg, 10mg, 500μg, 10 mg, 5 mg, 500 μg.
BRD4884 is a secondary carboxamide resulting from the formal condensation of the carboxy group of oxane-4-carboxylic acid with the 3-amino group of 4'-fluoro[1,1'-biphenyl]-3,4-diamine. It is a HDAC inhibitor (IC50 = 29 nM, 62 nM, and 1.09 M for HDAC1, HDAC2, and HDAC3, respectively) and has shown to enhance cognition in mouse models. It has a role as an EC 3.5.1.98 (histone deacetylase) inhibitor and a nootropic agent. It is a secondary carboxamide, a member of oxanes, a substituted aniline, a biaryl and a member of monofluorobenzenes.
Source: ChEBI
| Molecular formula | C18H19FN2O2 |
|---|---|
| Molecular weight | 314.4 g/mol |
| IUPAC name | N-[2-amino-5-(4-fluorophenyl)phenyl]oxane-4-carboxamide |
| InChIKey | ZFCDNONWGMYBHA-UHFFFAOYSA-N |
| SMILES | C1COCCC1C(=O)NC2=C(C=CC(=C2)C3=CC=C(C=C3)F)N |
Computed by PubChem (NCBI)
Synonyms:
N-(4-Amino-4'-fluoro[1,1'-biphenyl]-3-yl)tetrahydro-2H-pyran-4-carboxamide, N-(4-Amino-4'-Fluoro[1,1'-Biphenyl]-3-Yl)oxane-4-Carboxamide, N-(4-Amino-4'-fluoro-[1,1'-biphenyl]-3-yl)tetrahydro-2H-pyran-4-carboxamide, orb1703662, orb3032989, N-[2-amino-5-(4-fluorophenyl)phenyl]oxane-4-carboxamide, N-[2-amino-5-(4-fluorophenyl)phenyl]tetrahydropyran-4-carboxamide, N-(4-amino-4'-fluoro[biphenyl]-3-yl)tetrahydro-2H-pyran-4-carboxamide, 2H-Pyran-4-carboxamide, N-(4-amino-4'-fluoro[1,1'-biphenyl]-3-yl)tetrahydro-, IWX