CAS 1421373-66-1 appears in our catalog under these names: AZD-9291 Mesylate, >95% (HPLC), Osimertinib mesylate/ 99.53% (existing batch purity), AZD–9291 mesylate, AZD 9291 mesylate, Osimertinib mesylate, 98%. Offered by: TRC, TargetMol, GLPBio, Biosynth, Thermo Scientific (Acros). Available pack sizes: 100mg, 25mg, 50mg, 1g, 5mg, 10mg, 200mg, 500mg.
Osimertinib mesylate is a methanesulfonate (mesylate) salt prepared from equimolar amounts of osimertinib and methanesulfonic acid. It is used for treatment of EGFR T790M mutation positive non-small cell lung cancer. It has a role as an antineoplastic agent and an epidermal growth factor receptor antagonist. It contains an osimertinib(1+).
Source: ChEBI
| Molecular formula | C29H37N7O5S |
|---|---|
| Molecular weight | 595.7 g/mol |
| IUPAC name | N-[2-[2-(dimethylamino)ethyl-methylamino]-4-methoxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]phenyl]prop-2-enamide;methanesulfonic acid |
| InChIKey | FUKSNUHSJBTCFJ-UHFFFAOYSA-N |
| SMILES | CN1C=C(C2=CC=CC=C21)C3=NC(=NC=C3)NC4=C(C=C(C(=C4)NC(=O)C=C)N(C)CCN(C)C)OC.CS(=O)(=O)O |
Computed by PubChem (NCBI)