Products 1428-95-1
CAS 1428-95-1 appears in our catalog under these names: 5-(N,N-Hexamethylene)-amiloride, 99.14%, 5-(N,N-Hexamethylene)-amiloride (Standard), 3-Amino-5-(azepan-1-yl)-N-carbamimidoyl-6-chloropyrazine-2-carboxamide, 98%, 98%, 5-(N,N-Hexamethylene)-amiloride, 98%, 3-Amino-5-(azepan-1-yl)-N-carbamimidoyl-6-chloropyrazine-2-carboxamide, 98%. Offered by: MedChemExpress, Chemat, Ambeed, BLDpharm, Sigma-Aldrich. Available pack sizes: 50 mg, 100 mg, 10 mg, 10mM/1mL, 5 mg, 25 mg, 10mg, 50mg.
5-(N,N-hexamethylene)amiloride is a member of the class of pyrazines that is amiloride in which the two amino hydrogens at position N-5 are replaced by a hexamethylene moiety, resulting in the formation of an azepane ring. It has a role as an antineoplastic agent, a sodium channel blocker, an apoptosis inducer and an odorant receptor antagonist. It is a member of guanidines, a monocarboxylic acid amide, an aromatic amine, an organochlorine compound, a member of pyrazines and a member of azepanes. It is functionally related to an amiloride.
Source: ChEBI
| Molecular formula | C12H18ClN7O |
|---|---|
| Molecular weight | 311.77 g/mol |
| IUPAC name | 3-amino-5-(azepan-1-yl)-6-chloro-N-(diaminomethylidene)pyrazine-2-carboxamide |
| InChIKey | RQQJJXVETXFINY-UHFFFAOYSA-N |
| SMILES | C1CCCN(CC1)C2=NC(=C(N=C2Cl)C(=O)N=C(N)N)N |
Computed by PubChem (NCBI)
Synonyms:
5-(N,N-Hexamethylene)amiloride, Hexamethyleneamiloride, Hexamethylene amiloride, 3-Amino-6-chloro-5-(1-homopiperidyl)-N-(diaminomethylene)pyrazinecarboxamide, 5-(N,N-hexamethylene)-Amiloride, 3-amino-5-(azepan-1-yl)-N-carbamimidoyl-6-chloropyrazine-2-carboxamide, N,N-HEXAMETHYLENEAMILORIDE, HMA, 3-amino-5-(azepan-1-yl)-6-chloro-N-(diaminomethylidene)pyrazine-2-carboxamide, Spectrum2_001669