Products 142880-36-2
CAS 142880-36-2 appears in our catalog under these names: (R)-N1-((S)-3-(1H-Indol-3-yl)-1-(methylamino)-1-oxopropan-2-yl)-N4-hydroxy-2-isobutylsuccinamide, 95%+, Ilomastat, >95% (HPLC), GM 6001, Ilomastat/ 99.56% (existing batch purity), Galardinᵀᴹ. Offered by: Fluorochem, TRC, GLPBio, TargetMol, Biosynth. Available pack sizes: 5mg, 10mg, 25mg, 50mg, 250mg, 1mg, 10mM (in 1ml dmso), 2mg.
Ilomastat is an N-acyl-amino acid obtained by formal condensation of the carboxy group of (2R)-2-[2-(hydroxyamino)-2-oxoethyl]-4-methylpentanoic acid with the amino group of N-methyl-L-tryptophanamide. A cell permeable broad-spectrum matrix metalloproteinase (MMP) inhibitor. It has a role as an antibacterial agent, an antineoplastic agent, a neuroprotective agent, an anti-inflammatory agent and an EC 3.4.24.24 (gelatinase A) inhibitor. It is a hydroxamic acid, a L-tryptophan derivative and a N-acyl-amino acid.
Source: ChEBI
| Molecular formula | C20H28N4O4 |
|---|---|
| Molecular weight | 388.5 g/mol |
| IUPAC name | (2R)-N'-hydroxy-N-[(2S)-3-(1H-indol-3-yl)-1-(methylamino)-1-oxopropan-2-yl]-2-(2-methylpropyl)butanediamide |
| InChIKey | NITYDPDXAAFEIT-DYVFJYSZSA-N |
| SMILES | CC(C)C[C@H](CC(=O)NO)C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)NC |
Computed by PubChem (NCBI)