Products 145307-34-2
CAS 145307-34-2 appears in our catalog under these names: A 77636 hydrochloride/ 99.62% (existing batch purity), A 77636 hydrochloride, A-77636 HYDROCHLORIDE HYDRATE, A-77636 (hydrochloride), 99.57% ,, 99.57% ,, A-77636 (hydrochloride), 98.0%. Offered by: TargetMol, GLPBio, Sigma-Aldrich, Chemat, MedChemExpress. Available pack sizes: 1mg, 5mg, 10mg, 25mg, 50mg, 5 mg.
(1R,3S)-3-(adamantan-1-yl)-1-(aminomethyl)-3,4-dihydroisochromene-5,6-diol hydrochloride is a hydrochloride salt obtained by mixing equimolar amounts of (1R,3S)-3-(adamantan-1-yl)-1-(aminomethyl)-3,4-dihydroisochromene-5,6-diol with hydrochloric acid. Potent and selective dopamine D1-like receptor agonist (pEC50 values are 8.97 and < 5 for D1-like and D2-like receptors respectively). Displays anti-Parkinsonian activity following oral administration in vivo. It has a role as an antiparkinson drug and a dopamine agonist. It contains a (1R,3S)-3-(adamantan-1-yl)-1-(ammoniomethyl)-3,4-dihydroisochromene-5,6-diol(1+).
Source: ChEBI
| Molecular formula | C20H28ClNO3 |
|---|---|
| Molecular weight | 365.9 g/mol |
| IUPAC name | (1R,3S)-3-(1-adamantyl)-1-(aminomethyl)-3,4-dihydro-1H-isochromene-5,6-diol;hydrochloride |
| InChIKey | BWHPNJVKFAPVOG-QYFJGNGUSA-N |
| SMILES | C1[C@H](O[C@H](C2=C1C(=C(C=C2)O)O)CN)C34CC5CC(C3)CC(C5)C4.Cl |
Computed by PubChem (NCBI)