Products 1453834-21-3
CAS 1453834-21-3 appears in our catalog under these names: LDC 4297, LDC4297/ 98.25% (existing batch purity), LDC4297, N-(2-(1H-Pyrazol-1-yl)benzyl)-8-isopropyl-2-(piperidin-3-yloxy)pyrazolo[1,5-a][1,3,5]triazin-4-amine, 98.25% ,, 98.25% ,, LDC4297, 98.14%. Offered by: TRC, TargetMol, GLPBio, Biosynth, Chemat. Available pack sizes: 50mg, 1mg, 10mg, 25mg, 5mg, 25 mg, 5 mg, 10 mg.
LDC4297 is a pyrazolotriazine that is pyrazolo[1,5-a][1,3,5]triazine substituted by a piperidin-3-yloxy group, [2-(1H-pyrazol-1-yl)benzyl]nitrilo group and an isopropyl group at positions 2, 4 and 8 respectively. It is a potent and selective CDK7 inhibitor and exhibits antiviral activity. It has a role as an antiviral agent, an antineoplastic agent, an apoptosis inducer and an EC 2.7.11.22 (cyclin-dependent kinase) inhibitor. It is a pyrazolotriazine, a member of piperidines, a member of pyrazoles, an aromatic ether and a secondary amino compound.
Source: ChEBI
| Molecular formula | C23H28N8O |
|---|---|
| Molecular weight | 432.5 g/mol |
| IUPAC name | 2-piperidin-3-yloxy-8-propan-2-yl-N-[(2-pyrazol-1-ylphenyl)methyl]pyrazolo[1,5-a][1,3,5]triazin-4-amine |
| InChIKey | LSGRZENCFIIHNV-UHFFFAOYSA-N |
| SMILES | CC(C)C1=C2N=C(N=C(N2N=C1)NCC3=CC=CC=C3N4C=CC=N4)OC5CCCNC5 |
Computed by PubChem (NCBI)