Products 145599-86-6

CAS 145599-86-6 appears in our catalog under these names: (3R,5S,E)-7-(4-(4-Fluorophenyl)-2,6-diisopropyl-5-(methoxymethyl)pyridin-3-yl)-3,5-dihydroxyhept-6-enoic acid, 98+%, Cerivastatin, Cerivastatin/ 99.31% (existing batch purity). Offered by: Chemat Brand, TargetMol, Biosynth, Chemat, MedChemExpress. Available pack sizes: on request, 1mg, 5mg, 10mg, 25mg, 50mg, Get quote.

(3R,5S,E)-7-(4-(4-Fluorophenyl)-2,6-diisopropyl-5-(methoxymethyl)pyridin-3-yl)-3,5-dihydroxyhept-6-enoic acid, 98+%
Chemat Brand
  • size: on request
  • Variants: 1
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Cerivastatin
Chemat Brand, Biosynth, Chemat
  • size: on request, 5mg, 1mg, 10mg
  • Variants: 8
from 3218.00
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Cerivastatin/ 99.31% (existing batch purity)
TargetMol
  • size: 1mg, 5mg, 10mg, 25mg
  • Variants: 5
from 3082.20
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Cerivastatin is (3R,5S)-3,5-dihydroxyhept-6-enoic acid in which the (7E)-hydrogen is substituted by a 4-(4-fluorophenyl)-2,6-diisopropyl-5-(methoxymethyl)pyridin-3-yl group. Formerly used (as its sodium salt) to lower cholesterol and prevent cardiovascular disease, it was withdrawn from the market worldwide in 2001 following reports of a severe form of muscle toxicity. It is a member of pyridines, a dihydroxy monocarboxylic acid and a statin (synthetic). It is a conjugate acid of a cerivastatin(1-).

Source: ChEBI

Identity
Molecular formulaC26H34FNO5
Molecular weight459.5 g/mol
IUPAC name(E,3R,5S)-7-[4-(4-fluorophenyl)-5-(methoxymethyl)-2,6-di(propan-2-yl)-3-pyridinyl]-3,5-dihydroxyhept-6-enoic acid
InChIKeySEERZIQQUAZTOL-ANMDKAQQSA-N
SMILESCC(C)C1=C(C(=C(C(=N1)C(C)C)COC)C2=CC=C(C=C2)F)/C=C/[C@H](C[C@H](CC(=O)O)O)O

Computed by PubChem (NCBI)

Synonyms: cerivastatin, Lipobay, Cerivastatina, cerivastatinum, cerivastatin acid, Cerivastatin (INN), CERIVASTATIN [INN], Cerivastatin [INN:BAN], Cerivastatin, sodium salt, Cerivastatine