Products 150113-99-8
CAS 150113-99-8 appears in our catalog under these names: Decanoyl-Arg-Val-Lys-Arg-chloromethylketone, Decanoyl-RVKR-CMK, Decanoyl–RVKR–CMK, Decanoyl-RVKR-CMK 95%, Furin Inhibitor I 1PC X 150MG. Offered by: Creative Peptides, TargetMol, GLPBio, Ambeed, Sigma-Aldrich. Available pack sizes: on request, 1mg, 5mg, 10mg, 25mg, 50mg, 100mg, 150MG.
Decanoyl-L-Arg-L-Val-L-Lys-L-Arg-chloromethylketone is a tetrapeptide consisting of N-decanoyl-L-arginine, L-valine, L-lysine, and L-arginine joined in sequence by peptide linkages and in which the carboxy group at the C-terminus is substituted by a chloroacetyl group. It is a furin inhibitor that has antiviral activity against Chikungunya virus, Zika virus and Japanese encephalitis virus. It has a role as an EC 3.4.21.75 (furin) inhibitor, an antiviral agent and a peptidomimetic. It is an organochlorine compound and a tetrapeptide.
Source: ChEBI
| Molecular formula | C34H66ClN11O5 |
|---|---|
| Molecular weight | 744.4 g/mol |
| IUPAC name | N-[(2S)-1-[[(2S)-1-[[(2S)-6-amino-1-[[(3S)-1-chloro-6-(diaminomethylideneamino)-2-oxohexan-3-yl]amino]-1-oxohexan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]decanamide |
| InChIKey | NHBJTTGFHCHQHS-VZTVMPNDSA-N |
| SMILES | CCCCCCCCCC(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C(N)N)C(=O)CCl |
Computed by PubChem (NCBI)
Synonyms:
Decanoyl-RVKR-CMK, decanoyl-RVKR-chloromethylketone, DECANOYL-ARG-VAL-LYS-ARG-CHLOROMETHYLKETONE, Furin-IN-I, decanoyl-Arg-Val-Lys-Arg-CMK, decanoyl-Arg-Val-Lys-Arg-chloromethyl ketone, Dec-RVKR-CMK, DecRVKRcmk, Furin Inhibitor I, Decanoyl-Arg-Val-Lys-Arg-chloromethylketone trifluoroacetate salt