Products 151555-47-4

CAS 151555-47-4 appears in our catalog under these names: RU 58668, RU 58668, RU58668. Offered by: Chemat Brand, GLPBio, MedChemExpress. Available pack sizes: on request, 10mg, Get quote.

RU 58668 is a 17beta-hydroxy steroid that is 17beta-estradiol in the the hydrogen at the 11beta position has been replaced by a p-({5-[(4,4,5,5,5-pentafluoropentyl)sulfonyl]pentyl}oxy)phenyl group. RU 58668 is a pure anti-estrogen that downregulates estrogen receptor expression (IC50 = 0.04 nM). It has a role as an antineoplastic agent, an anti-estrogen and an estrogen receptor antagonist. It is a 17beta-hydroxy steroid, an aromatic ether, a sulfone, a 3-hydroxy steroid and an organofluorine compound.

Source: ChEBI

Identity
Molecular formulaC34H43F5O5S
Molecular weight658.8 g/mol
IUPAC name(8S,9R,11S,13S,14S,17S)-13-methyl-11-[4-[5-(4,4,5,5,5-pentafluoropentylsulfonyl)pentoxy]phenyl]-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol
InChIKeySDCUWFRXMLQNCS-LFAPAAFUSA-N
SMILESC[C@]12C[C@@H]([C@H]3[C@H]([C@@H]1CC[C@@H]2O)CCC4=C3C=CC(=C4)O)C5=CC=C(C=C5)OCCCCCS(=O)(=O)CCCC(C(F)(F)F)(F)F

Computed by PubChem (NCBI)