Products 152044-53-6

CAS 152044-53-6 appears in our catalog under these names: Ixabepilone Impurity 5 (Epothilone A), Epothilone A, >95% (HPLC), Epothilone A, Epothilone A/ 98.27% (existing batch purity), (1S,3S,7S,10R,11S,12S,16R)-7,11-Dihydroxy-8,8,10,12-tetramethyl-3-[(1E)-1-methyl-2-(2-methyl-4-thiazolyl)ethenyl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione, 98%, 98%. Offered by: Chemat Brand, TRC, GLPBio, TargetMol, Chemat. Available pack sizes: on request, 10mg, 1mg, 50mg, 100mg, 25mg, 5mg, 10mM (in 1ml dmso).

Ixabepilone Impurity 5 (Epothilone A)
Chemat Brand
  • size: on request
  • Variants: 1
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Epothilone A, >95% (HPLC)
TRC
  • size: 10mg, 1mg, 50mg
  • Variants: 3
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Epothilone A
GLPBio
  • size: 100mg, 25mg, 5mg, 10mM (in 1ml dmso)
  • Variants: 4
from 742.14
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Epothilone A/ 98.27% (existing batch purity)
TargetMol
  • size: 5mg, 10mg, 25mg, 50mg
  • Variants: 6
from 465.53
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(1S,3S,7S,10R,11S,12S,16R)-7,11-Dihydroxy-8,8,10,12-tetramethyl-3-[(1E)-1-methyl-2-(2-methyl-4-thiazolyl)ethenyl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione, 98%, 98%
Chemat
  • size: 25mg, 50mg, 100mg
  • Variants: 3
from 443.60
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Epothilone A, 99.81%
MedChemExpress
  • size: 10 mg, 25 mg, 50 mg, 5 mg
  • Variants: 6
from 551.89
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Epothilone A (Standard)
MedChemExpress
  • size: Get quote
  • Variants: 1
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EPOTHILONE A, 98%
Fluorochem
  • size: 25mg, 50mg, 100mg
  • Variants: 3
from 732.05
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Structural formula: {0} (CAS {1})

Epothilone A is an epithilone that is epothilone C in which the double bond in the macrocyclic lactone ring has been oxidised to the corresponding epoxide (the 13R,14S diastereoisomer). It has a role as a metabolite, an antineoplastic agent, a tubulin modulator and a microtubule-stabilising agent. It is an epoxide and an epothilone.

Source: ChEBI

Identity
Molecular formulaC26H39NO6S
Molecular weight493.7 g/mol
IUPAC name(1S,3S,7S,10R,11S,12S,16R)-7,11-dihydroxy-8,8,10,12-tetramethyl-3-[(E)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione
InChIKeyHESCAJZNRMSMJG-KKQRBIROSA-N
SMILESC[C@H]1CCC[C@@H]2[C@@H](O2)C[C@H](OC(=O)C[C@@H](C(C(=O)[C@@H]([C@H]1O)C)(C)C)O)/C(=C/C3=CSC(=N3)C)/C

Computed by PubChem (NCBI)

Synonyms: Epothilone A, (-)-Epothilone A, Epo A, Epothilon A, Epoa, Epothilone A [MI], Epothilone-A, Epothilones, EpothiloneA, EPOTHILONE A [WHO-DD]