Products 152459-95-5

CAS 152459-95-5 appears in our catalog under these names: Imatinib, >95% (HPLC), Imatinib, Imatinib (STI571), Imatinib/ 99.85% (existing batch purity), Imatinib base. Offered by: TRC, Chemat Brand, Mikromol, Dr. Ehrenstorfer, GLPBio. Available pack sizes: 100mg, 1g, 500mg, on request, 10mM (in 1ml dmso), 5g, 200mg, 0,025kg.

Imatinib, >95% (HPLC)
TRC
  • size: 100mg, 1g, 500mg
  • Variants: 3
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Imatinib
Chemat Brand, Mikromol, Dr. Ehrenstorfer
  • size: on request, 100mg, 1x100mg
  • Variants: 4
from 708.88
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Imatinib (STI571)
GLPBio
  • size: 100mg, 10mM (in 1ml dmso)
  • Variants: 2
from 578.32
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Imatinib/ 99.85% (existing batch purity)
TargetMol
  • size: 1g, 5g, 100mg, 200mg
  • Variants: 5
from 425.84
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Imatinib base
Biosynth
  • size: 0,025kg, 0,05kg, 0,1kg, 0,25kg
  • Variants: 5
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Imatinib base - Bio-X â„¢
Biosynth
  • size: 100mg
  • Variants: 1
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Imatinib, >98.0%(HPLC)
TCI
  • size: 100mg, 1g
  • Variants: 2
from 221.61
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4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide, 98%, 98%
Chemat
  • size: 1g, 5g, 10g, 25g
  • Variants: 7
from 78.80
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Imatinib, 99.95%
MedChemExpress
  • size: 500 mg, 10 g, 200 mg, 5 g
  • Variants: 6
from 435.79
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Imatinib (Standard), 99.92%
MedChemExpress
  • size: 50 mg, 10 mg, 25 mg, 100 mg
  • Variants: 4
from 310.40
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Imatinib, 98%
Fluorochem
  • size: 1g, 5g, 10g, 25g
  • Variants: 6
from 112.48
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Structural formula: {0} (CAS {1})

Imatinib is a benzamide obtained by formal condensation of the carboxy group of 4-[(4-methylpiperazin-1-yl)methyl]benzoic acid with the primary aromatic amino group of 4-methyl-N3-[4-(pyridin-3-yl)pyrimidin-2-yl]benzene-1,3-diamine. Used (as its mesylate salt) for treatment of chronic myelogenous leukemia and gastrointestinal stromal tumours. It has a role as an antineoplastic agent, a tyrosine kinase inhibitor and an apoptosis inducer. It is a member of benzamides, a member of pyridines, an aromatic amine, a member of pyrimidines and a N-methylpiperazine. It is functionally related to a benzamide.

Source: ChEBI

Identity
Molecular formulaC29H31N7O
Molecular weight493.6 g/mol
IUPAC name4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide
InChIKeyKTUFNOKKBVMGRW-UHFFFAOYSA-N
SMILESCC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC=CC(=N4)C5=CN=CC=C5

Computed by PubChem (NCBI)

Synonyms: Imatinib, Glamox, Imatinibum, Imatinib (STI571), Imatinib free base, Imatinib (INN), Imatinib Methansulfonate, imatinib-CD3, IMATINIB [INN], Imatinib [INN:BAN]
Related forms of this compound
N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]-4-[(2,2,3,3,5,5,6,6-octadeuterio-4-methylpiperazin-1-yl)methyl]benzamide C29H31N7O
N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]-4-[[4-(trideuteriomethyl)piperazin-1-yl]methyl]benzamide C29H31N7O
Isomers (same molecular formula)
3-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide C29H31N7O
4-[(4-methylpiperazin-1-yl)methyl]-N-[3-methyl-4-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide C29H31N7O