Products 157283-68-6

CAS 157283-68-6 appears in our catalog under these names: Travoprost, 95%, Travoprost, Travoprost, >95% (HPLC), Travoprost/ 99.35% (existing batch purity), Travoprost, >98.0%(HPLC)(qNMR). Offered by: Combi-blocks, Chemat Brand, TRC, Mikromol, TargetMol. Available pack sizes: 250mg, 100mg, 1g, on request, 10mg, 25mg, 50mg, 1mg.

Structural formula: {0} (CAS {1})

Travoprost is the isopropyl ester of prostaglandin F2alpha in which the pentyl group is replaced by a 3-(trifluoromethyl)phenoxymethyl group. A synthetic analogue of prostaglandin F2alpha, ophthalmic solutions of travoprost are used as a topical medication for controlling the progression of open-angle glaucoma and ocular hypertension, by reducing intraocular pressure. It is a pro-drug; the isopropyl ester group is hydrolysed by esterases in the cornea to the biologically active free acid, fluprostenol. It has a role as an antihypertensive agent, an antiglaucoma drug, a prodrug, a prostaglandin receptor agonist and an ophthalmology drug. It is an isopropyl ester, a prostaglandins Falpha and a member of (trifluoromethyl)benzenes. It is functionally related to a fluprostenol.

Source: ChEBI

Identity
Molecular formulaC26H35F3O6
Molecular weight500.5 g/mol
IUPAC namepropan-2-yl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-enyl]cyclopentyl]hept-5-enoate
InChIKeyMKPLKVHSHYCHOC-AHTXBMBWSA-N
SMILESCC(C)OC(=O)CCC/C=C\C[C@H]1[C@H](C[C@H]([C@@H]1/C=C/[C@H](COC2=CC=CC(=C2)C(F)(F)F)O)O)O

Computed by PubChem (NCBI)