Products 1613191-99-3
CAS 1613191-99-3 appears in our catalog under these names: 2-Amino-6-fluoro-N-[5-fluoro-4-[4-[[4-(3-oxetanyl)-1-piperazinyl]carbonyl]-1-piperidinyl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide, 98%, 2-Amino-6-fluoro-N-(5-fluoro-4-(4-(4-(oxetan-3-yl)piperazine-1-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide, 98%, ATR inhibitor 2, Atr inhibitor 2, Gartisertib, 99.77%. Offered by: Chemat, BLDpharm, GLPBio, Biosynth, MedChemExpress. Available pack sizes: 5mg, 10mg, 25mg, 50mg, 100mg, 250mg, 1g, 10mM/1mL.
Gartisertib is a member of the class of pyrazolopyrimidines that is pyrazolo[1,5-a]pyrimidine substituted by amino, N-[5-fluoro-4-(4-{[4-(oxetan-3-yl)piperazin-1-yl]carbonyl}piperidin-1-yl)pyridin-3-yl]aminoacyl, and fluoro groups at positions 2, 3 and 6, respectively. It is an inhibitor of ataxia telangiectasia and Rad3 related (ATR) kinase that exhibits antineoplastic activity. It has a role as an antineoplastic agent, an EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor and an EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor. It is a secondary carboxamide, a member of pyridines, an aromatic amine, an organofluorine compound, a pyrazolopyrimidine, a member of oxetanes, a N-acylpiperazine, a piperidinecarboxamide and a primary amino compound.
Source: ChEBI
| Molecular formula | C25H29F2N9O3 |
|---|---|
| Molecular weight | 541.6 g/mol |
| IUPAC name | 2-amino-6-fluoro-N-[5-fluoro-4-[4-[4-(oxetan-3-yl)piperazine-1-carbonyl]piperidin-1-yl]-3-pyridinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide |
| InChIKey | QAYHKBLKSXWOEO-UHFFFAOYSA-N |
| SMILES | C1CN(CCC1C(=O)N2CCN(CC2)C3COC3)C4=C(C=NC=C4NC(=O)C5=C6N=CC(=CN6N=C5N)F)F |
Computed by PubChem (NCBI)