Products 1616632-77-9

CAS 1616632-77-9 appears in our catalog under these names: ONC201, 7-Benzyl-4-(2-methylbenzyl)-1,2,6,7,8,9-hexahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(4H)-one, 99+%, TIC10/ 99.72% (existing batch purity), TIC10, TIC10, 99+%. Offered by: Chemat Brand, GLPBio, TargetMol, Biosynth, Fluorochem. Available pack sizes: on request, 10mg, 100mg, 5mg, 50mg, 1g, 25mg, 200mg.

ONC201
Chemat Brand, GLPBio
  • size: on request, 10mg, 100mg, 5mg
  • Variants: 5
from 583.00
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7-Benzyl-4-(2-methylbenzyl)-1,2,6,7,8,9-hexahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(4H)-one, 99+%
Chemat Brand
  • size: on request
  • Variants: 1
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TIC10/ 99.72% (existing batch purity)
TargetMol
  • size: 1g, 5mg, 10mg, 25mg
  • Variants: 8
from 511.92
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TIC10
Biosynth
  • size: 100mg, 50mg, 250mg, 500mg
  • Variants: 4
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TIC10, 99+%
Fluorochem
  • size: 25mg, 50mg, 100mg, 250mg
  • Variants: 5
from 247.85
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Structural formula: {0} (CAS {1})

Dordaviprone is an organic heterotricyclic compound that is 2,4,6,7,8,9-hexahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(1H)-one substituted by 2-methylbenzyl and benzyl groups at positions 4 and 7, respectively. It is a selective antagonist of the dopamine receptor D2 and an allosteric agonist of mitochondrial protease caseinolytic protease P. It has a role as a dopamine receptor D2 antagonist, an antineoplastic agent and an apoptosis inducer. It is a member of benzenes, an organic heterotricyclic compound and a member of toluenes.

Source: ChEBI

Identity
Molecular formulaC24H26N4O
Molecular weight386.5 g/mol
IUPAC name11-benzyl-7-[(2-methylphenyl)methyl]-2,5,7,11-tetrazatricyclo[7.4.0.02,6]trideca-1(9),5-dien-8-one
InChIKeyVLULRUCCHYVXOH-UHFFFAOYSA-N
SMILESCC1=CC=CC=C1CN2C(=O)C3=C(CCN(C3)CC4=CC=CC=C4)N5C2=NCC5

Computed by PubChem (NCBI)

Synonyms: Dordaviprone, Akt/ERK Inhibitor ONC201, dordaviprona, TRAIL-inducing Compound 10, Modeyso, dordavipronum, Angular TIC10, dordaviprone [INN], Dordaviprone (USAN/INN), DORDAVIPRONE [USAN]
Isomers (same molecular formula)
11-benzyl-4-[(2-methylphenyl)methyl]-2,4,7,11-tetrazatricyclo[7.4.0.03,7]trideca-1(9),2-dien-8-one C24H26N4O
11-benzyl-2-[(2-methylphenyl)methyl]-2,4,7,11-tetrazatricyclo[7.4.0.03,7]trideca-1(9),3-dien-8-one C24H26N4O