Products 1632051-40-1

CAS 1632051-40-1 is the registry number for SAGE-217. Offered by: Hubei YoungXin, Biosynth. Available pack sizes: 10mg, 25mg, 50mg, 100mg, 200mg.

SAGE-217
Hubei YoungXin, Biosynth
  • size: 10mg, 25mg, 50mg, 100mg
  • Variants: 8
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Structural formula: {0} (CAS {1})

Zuranolone is a 3-hydroxy steroid that is 5beta-19-norpregnane substituted by hydroxy, methyl, oxo, and 4-cyano-1H-pyrazol-1-yl groups at positions 3, 3, 20 and 21, respectively. It is a positive allosteric modulator of GABAA receptor developed by Sage Therapeutics and Biogen for the treatment of postpartum depression in adults. It has a role as an antidepressant, an anticonvulsant and a GABA modulator. It is a nitrile, a member of pyrazoles, a 3-hydroxy steroid and a 20-oxo steroid.

Source: ChEBI

Identity
Molecular formulaC25H35N3O2
Molecular weight409.6 g/mol
IUPAC name1-[2-[(3R,5R,8R,9R,10S,13S,14S,17S)-3-hydroxy-3,13-dimethyl-2,4,5,6,7,8,9,10,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl]pyrazole-4-carbonitrile
InChIKeyHARRKNSQXBRBGZ-GVKWWOCJSA-N
SMILESC[C@]1(CC[C@H]2[C@@H](C1)CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CC[C@@H]4C(=O)CN5C=C(C=N5)C#N)C)O

Computed by PubChem (NCBI)

Synonyms: Zuranolone, Zurzuvae, zuranolonum, 3beta-Methyl-21-(4-cyano-1H-pyrazol-1'-yl)-19-norpregnanolone, Zuranolone [INN], Zuranolone [USAN], ZuranoloneSAGE-217, Zurzuvae (TN), Zuranolone [WHO-DD], Zuranolone [USAN:INN]