Products 164656-23-9

CAS 164656-23-9 appears in our catalog under these names: Dutasteride, 98%, Dutasteride, Dutasteride, >95% (HPLC), Dutasteride/ 99.68% (existing batch purity), Dutasteride - Bio-X â„¢. Offered by: Combi-blocks, Chemat Brand, Hubei YoungXin, TRC, Mikromol. Available pack sizes: 25g, 5g, 10g, 1g, 250mg, on request, 10mg, 25mg.

Dutasteride, 98%
Combi-blocks, Thermo Scientific (Acros)
  • size: 25g, 5g, 10g, 1g
  • Variants: 7
from 579.08
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Dutasteride
Chemat Brand, Hubei YoungXin, Mikromol
  • size: on request, 10mg, 25mg, 50mg
  • Variants: 17
from 578.32
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Dutasteride, >95% (HPLC)
TRC
  • size: 100mg, 1g, 5mg
  • Variants: 3
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Dutasteride/ 99.68% (existing batch purity)
TargetMol
  • size: 5mg, 10mg, 25mg, 50mg
  • Variants: 7
from 399.00
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Dutasteride - Bio-X â„¢
Biosynth
  • size: 10mg
  • Variants: 1
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Dutasteride, >98.0%(HPLC)
TCI
  • size: 500mg
  • Variants: 1
from 1121.46
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Dutasteride, 98.00%
Chemat
  • size: 1g
  • Variants: 1
from 1203.83
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(5α,17β)-N-[2,5-Bis(trifluoromethyl)phenyl]-3-oxo-4- Aza -androst-1-ene-17-carboxamide, 98%, 98%
Chemat
  • size: 100mg, 250mg, 1g
  • Variants: 3
from 98.00
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Dutasteride, 95%
Fluorochem
  • size: 250mg, 1g
  • Variants: 2
from 216.61
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Dutasteride, min. 95 %, 2 g
Roth
  • size: 2g
  • Variants: 1
from 2430.60
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Dutasteride, min. 95 %, 5 g
Roth
  • size: 5g
  • Variants: 1
from 3374.52
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Dutasteride, min. 95 %, 10 g
Roth
  • size: 10g
  • Variants: 1
from 5375.63
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Dutasteride, min. 95 %, 25 g
Roth
  • size: 25g
  • Variants: 1
from 8726.54
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Dutasteride, min. 95 %, BioScience Grade, 10 mg
Roth
  • size: 10mg
  • Variants: 1
from 495.56
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Dutasteride, 99.75%
MedChemExpress
  • size: 100 mg, 10mM/1mL, 10 mg, 5 mg
  • Variants: 5
from 319.69
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Dutasteride (Standard)
MedChemExpress
  • size: 25 mg, 5 mg, 100 mg, 10 mg
  • Variants: 5
from 524.03
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Structural formula: {0} (CAS {1})

Dutasteride is an aza-steroid that is inasteride in which the tert-butyl group is replaced by a 2,5-bis(trifluoromethyl)phenyl group. A synthetic 4-azasteroid, dutasteride is a selective inhibitor of both the type 1 and type 2 isoforms of steroid 5alpha-reductase, an intracellular enzyme that converts testosterone to 5alpha-dihydrotestosterone. Dutasteride is used for the treatment of symptomatic benign prostatic hyperplasia in men with an enlarged prostate gland. It has a role as an EC 1.3.1.22 [3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+))] inhibitor and an antihyperplasia drug. It is an aza-steroid, a delta-lactam and a member of (trifluoromethyl)benzenes. It derives from a hydride of a 5alpha-androstane.

Source: ChEBI

Identity
Molecular formulaC27H30F6N2O2
Molecular weight528.5 g/mol
IUPAC name(1S,3aS,3bS,5aR,9aR,9bS,11aS)-N-[2,5-bis(trifluoromethyl)phenyl]-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide
InChIKeyJWJOTENAMICLJG-QWBYCMEYSA-N
SMILESC[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2C(=O)NC4=C(C=CC(=C4)C(F)(F)F)C(F)(F)F)CC[C@@H]5[C@@]3(C=CC(=O)N5)C

Computed by PubChem (NCBI)

Synonyms: Dutasteride, Avodart, Avolve, Duastride, Dutasterida, JALYN COMPONENT DUTASTERIDE, dutasteridum, Duagen, Dutasteride [USAN], Avodart (TN)
Related forms of this compound
(1S,3aS,3bS,5aS,9aR,9bS,11aS)-N-[2,5-bis(trifluoromethyl)phenyl]-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide C27H30F6N2O2
(1S,3aS,3bS,5aR,9aR,9bS,11aS)-9a,11a-dimethyl-7-oxo-N-[2,4,5-trideuterio-3,6-bis(trifluoromethyl)phenyl]-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide C27H30F6N2O2
(1R,3aS,3bS,5aR,9aR,9bS,11aS)-N-[2,5-bis(trifluoromethyl)phenyl]-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide C27H30F6N2O2
(1R,3aS,3bS,5aR,9aR,9bS,11aS)-N-[2,5-bis(trifluoromethyl)phenyl]-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide C27H30F6N2O2
(1S,3aS,3bS,5aR,9aR,9bS,11aS)-N-[2,5-bis(trifluoromethyl)(1,2,3,4,5,6-13C6)cyclohexa-1,3,5-trien-1-yl]-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide C27H30F6N2O2
Isomers (same molecular formula)
(1S,3aS,3bS,9aR,9bS,11aS)-N-[2,5-bis(trifluoromethyl)phenyl]-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,6,8,9,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide C27H30F6N2O2