Products 1681056-61-0

CAS 1681056-61-0 appears in our catalog under these names: OSMI 1, OSMI-1/ 99.83% (existing batch purity), OSMI–1, OSMI-1 98%, (αR)-α-[[(1,2-Dihydro-2-oxo-6-quinolinyl)sulfonyl]amino]-N-(2-furanylmethyl)-2-methoxy-N-(2-thienylmethyl)benzeneacetamide, 98%, 98%. Offered by: TRC, TargetMol, GLPBio, Biosynth, Ambeed. Available pack sizes: 10mg, 1mg, 5mg, 2mg, 25mg, 50mg, 100mg, 10mM (in 1ml dmso).

OSMI 1
TRC, Biosynth
  • size: 10mg, 1mg, 5mg, 50mg
  • Variants: 6
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OSMI-1/ 99.83% (existing batch purity)
TargetMol
  • size: 1mg, 2mg, 5mg, 10mg
  • Variants: 7
from 412.42
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OSMI–1
GLPBio
  • size: 10mg, 10mM (in 1ml dmso), 25mg, 5mg
  • Variants: 5
from 793.62
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OSMI-1 98%
Ambeed
  • size: 5mg, 10mg, 25mg, 50mg
  • Variants: 7
from 414.88
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(αR)-α-[[(1,2-Dihydro-2-oxo-6-quinolinyl)sulfonyl]amino]-N-(2-furanylmethyl)-2-methoxy-N-(2-thienylmethyl)benzeneacetamide, 98%, 98%
Chemat
  • size: 5mg, 10mg, 25mg
  • Variants: 3
from 328.40
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OSMI-1, 99.90%
MedChemExpress
  • size: 10mM/1mL, 100 mg, 25 mg, 50 mg
  • Variants: 8
from 593.69
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(R)-N-(Furan-2-ylmethyl)-2-(2-methoxyphenyl)-2-(2-oxo-1,2-dihydroquinoline-6-sulfonamido)-N-(thiophen-2-ylmethyl)acetamide, 98%
Fluorochem
  • size: 5mg, 10mg, 25mg
  • Variants: 3
from 601.89
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Structural formula: {0} (CAS {1})

OSMI-1 is a sulfonamide resulting from the formal condensation of the sulfonic acid group of 2-oxo-1,2-dihydroquinoline-6-sulfonic acid with the primary amino group of (2R)-2-amino-N-(2-furylmethyl)-2-(2-methoxyphenyl)-N-(2-thienylmethyl)acetamide. OSMI-1 is a cell permeable inhibitor of O-linked beta-N-acetylglucosamine transferase (O-GlcNAc transferase, OGT). It has a role as an EC 2.4.1.255 (protein O-GlcNAc transferase) inhibitor and an EC 2.* (transferase) inhibitor. It is a tertiary carboxamide, a member of furans, a member of quinolines, a member of thiophenes, a sulfonamide and an aromatic ether.

Source: ChEBI

Identity
Molecular formulaC28H25N3O6S2
Molecular weight563.6 g/mol
IUPAC name(2R)-N-(furan-2-ylmethyl)-2-(2-methoxyphenyl)-2-[(2-oxo-1H-quinolin-6-yl)sulfonylamino]-N-(thiophen-2-ylmethyl)acetamide
InChIKeyIYIGLWQQAMROOF-HHHXNRCGSA-N
SMILESCOC1=CC=CC=C1[C@H](C(=O)N(CC2=CC=CO2)CC3=CC=CS3)NS(=O)(=O)C4=CC5=C(C=C4)NC(=O)C=C5

Computed by PubChem (NCBI)

Synonyms: ylmethyl)acetamide, orb1218661, orb1307925, 1,2-dihydroquinoline-6-sulfonamido)-N-(thiophen-2-, (R)-N-(Furan-2-ylmethyl)-2-(2-methoxyphenyl)-2-(2-oxo-