Products 1793053-37-8
CAS 1793053-37-8 appears in our catalog under these names: LLY-507, LLY507, LLY 507, LLY-507, 97%, 97%, LLY-507, 99.09%. Offered by: TRC, TargetMol, GLPBio, Biosynth, Chemat. Available pack sizes: 500mg, 1mg, 2mg, 5mg, 10mg, 25mg, 50mg, 100mg.
LLY-507 is a secondary carboxamide resulting from the formal condensation of the carboxy group of 5-cyano-2'-{4-[2-(3-methyl-1H-indol-1-yl)ethyl]piperazin-1-yl}[biphenyl]-3-carboxylic acid with the amino group of 3-(pyrrolidin-1-yl)propan-1-amine. It is a potent and selective inhibitor of SMYD2 and inhibits the ability of SMYD2 to methylate p53. It serves as a valuable chemical probe to aid in the dissection of SMYD2 function in cancer and other biological processes. It has a role as an EC 2.1.1.354 ([histone H3]-lysine(4) N-trimethyltransferase) inhibitor. It is a secondary carboxamide, a nitrile, a member of benzamides, a methylindole, a N-alkylpyrrolidine, a N-alkylpiperazine and a N-arylpiperazine.
Source: ChEBI
| Molecular formula | C36H42N6O |
|---|---|
| Molecular weight | 574.8 g/mol |
| IUPAC name | 3-cyano-5-[2-[4-[2-(3-methylindol-1-yl)ethyl]piperazin-1-yl]phenyl]-N-(3-pyrrolidin-1-ylpropyl)benzamide |
| InChIKey | PNYRDVBFYVDJJI-UHFFFAOYSA-N |
| SMILES | CC1=CN(C2=CC=CC=C12)CCN3CCN(CC3)C4=CC=CC=C4C5=CC(=CC(=C5)C#N)C(=O)NCCCN6CCCC6 |
Computed by PubChem (NCBI)