Products 1809249-37-3

CAS 1809249-37-3 appears in our catalog under these names: Remdesivir, Remdesivir/ 99.93% (existing batch purity), Remdesivir (GS–5734), Remdesivir, 98.00%, 2-ethylbutyl (2S)-2-[[[(2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxyoxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate, 99%, 99%. Offered by: Chemat Brand, Mikromol, TargetMol, GLPBio, Biosynth. Available pack sizes: on request, 250mg, 1mg, 5mg, 10mg, 25mg, 50mg, 100mg.

Structural formula: {0} (CAS {1})

Remdesivir is a carboxylic ester resulting from the formal condensation of the carboxy group of N-[(S)-{[(2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl]methoxy}(phenoxy)phosphoryl]-L-alanine with the hydroxy group of 2-ethylbutan-1-ol. A broad-spectrum antiviral prodrug with potent in vitro antiviral activity against a diverse panel of RNA viruses such as Ebola virus, MERS-CoV and SARS-CoV. It is currently in Phase III clinical trials for the treatment of Covid-19 in adults. It has a role as an anticoronaviral agent, an antiviral drug and a prodrug. It is a nitrile, a phosphoramidate ester, a carboxylic ester, an aromatic amine, a C-nucleoside and a pyrrolotriazine. It is functionally related to a GS-441524.

Source: ChEBI

Identity
Molecular formulaC27H35N6O8P
Molecular weight602.6 g/mol
IUPAC name2-ethylbutyl (2S)-2-[[[(2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxyoxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate
InChIKeyRWWYLEGWBNMMLJ-YSOARWBDSA-N
SMILESCCC(CC)COC(=O)[C@H](C)N[P@](=O)(OC[C@@H]1[C@H]([C@H]([C@](O1)(C#N)C2=CC=C3N2N=CN=C3N)O)O)OC4=CC=CC=C4

Computed by PubChem (NCBI)