Products 181223-80-3
CAS 181223-80-3 appears in our catalog under these names: N-(3-((5-Methoxy-1H-indol-3-yl)methylene)-2-oxoindolin-5-yl)-3-(piperidin-1-yl)propanamide, 98%, DEL-22379/ 100%, DEL–22379, DEL-22379, 99.69%, DEL-22379, 98%. Offered by: BLDpharm, TargetMol, GLPBio, MedChemExpress, Chemat. Available pack sizes: 10mg, 25mg, 100mg, 1mg, 2mg, 5mg, 50mg, 5 mg.
DEL-22379 is an oxindole that is 5-amino-oxindole in which the 5-amino group has undergone formal condensation with the carboxy group of 3-(piperidin-1-yl)propanoic acid to give the corresponding carboxamide and in which the hydrogens at position 3 have been replaced by a (5-methoxy-1H-indol-3-yl)methylene group (Z configuration). It is an inhibitor of extracellular signal-regulated kinase (ERK) dimerisation. It has a role as an antineoplastic agent and an ERK dimerisation inhibitor. It is a secondary carboxamide, a member of piperidines, a member of oxindoles and an enamide.
Source: ChEBI
| Molecular formula | C26H28N4O3 |
|---|---|
| Molecular weight | 444.5 g/mol |
| IUPAC name | N-[(3Z)-3-[(5-methoxy-1H-indol-3-yl)methylidene]-2-oxo-1H-indol-5-yl]-3-piperidin-1-ylpropanamide |
| InChIKey | INQUULPXCZAKMS-XKZIYDEJSA-N |
| SMILES | COC1=CC2=C(C=C1)NC=C2/C=C\3/C4=C(C=CC(=C4)NC(=O)CCN5CCCCC5)NC3=O |
Computed by PubChem (NCBI)