Products 1816989-16-8

CAS 1816989-16-8 appears in our catalog under these names: N-((1S,3R)-3-((5-Chloro-4-(1H-indol-3-yl)-2-pyrimidinyl)amino)-1-methylcyclohexyl)-5-(((2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl)amino)-2-pyridinecarboxamide, Mevociclib/ 98.02% (existing batch purity), Mevociclib, Mevociclib, 99.27%. Offered by: TRC, TargetMol, Biosynth, Chemat, MedChemExpress. Available pack sizes: 25mg, 1mg, 10mg, 50mg, 5mg, 5 mg, 100 mg, 50 mg.

N-((1S,3R)-3-((5-Chloro-4-(1H-indol-3-yl)-2-pyrimidinyl)amino)-1-methylcyclohexyl)-5-(((2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl)amino)-2-pyridinecarboxamide
TRC
  • size: 25mg
  • Variants: 1
View product
Mevociclib/ 98.02% (existing batch purity)
TargetMol
  • size: 1mg
  • Variants: 1
from 1454.96
View product
Mevociclib
Biosynth, Chemat
  • size: 10mg, 25mg, 50mg, 1mg
  • Variants: 6
from 947.60
View product
Mevociclib, 99.27%
MedChemExpress
  • size: 5 mg, 100 mg, 50 mg, 10 mg
  • Variants: 6
from 914.12
View product
Structural formula: {0} (CAS {1})

Mevociclib (SY-1365) is a selective CDK7 inhibitor. Mevociclib exhibits anti-proliferative and apoptotic effects in solid tumor cell lines. Mevociclib possesses anti-tumor activity in hematological and multiple aggressive solid tumors.

Source: ChEBI

Identity
Molecular formulaC31H35ClN8O2
Molecular weight587.1 g/mol
IUPAC nameN-[(1S,3R)-3-[[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]-1-methylcyclohexyl]-5-[[(E)-4-(dimethylamino)but-2-enoyl]amino]pyridine-2-carboxamide
InChIKeySCJNYBYSTCRPAO-LXBQGUBHSA-N
SMILESC[C@@]1(CCC[C@H](C1)NC2=NC=C(C(=N2)C3=CNC4=CC=CC=C43)Cl)NC(=O)C5=NC=C(C=C5)NC(=O)/C=C/CN(C)C

Computed by PubChem (NCBI)

Synonyms: Mevociclib, Mevociclib [INN], 1816989-16-8 (free base), Mevociclib [WHO-DD], orb1708442, compound 264 [WO2015154039A2]