Products 183499-57-2
CAS 183499-57-2 appears in our catalog under these names: L-778123 free base, L–778,123, L-778123, 99.92%, 4-((5-((4-(3-Chlorophenyl)-3-oxopiperazin-1-yl)methyl)-1H-imidazol-1-yl)methyl)benzonitrile, 98%. Offered by: TargetMol, GLPBio, MedChemExpress, Chemat. Available pack sizes: 5mg, 10mg, 25mg, 50mg, 1mg, 5 mg, 50 mg, 100 mg.
L-778,123 (free base) is a member of the class of imidazoles that is 1H-imidazole substituted by (4-cyanophenyl)methyl and [4-(3-chlorophenyl)-3-oxopiperazin-1-yl]methyl groups at positions 1 and 5, respectively. It is a dual inhibitor of FPTase and GGPTase-I. It has a role as an antineoplastic agent, an EC 2.5.1.58 (protein farnesyltransferase) inhibitor and an EC 2.5.1.59 (protein geranylgeranyltransferase type I) inhibitor. It is a nitrile, a member of imidazoles, a piperazinone, a tertiary amino compound and a member of monochlorobenzenes.
Source: ChEBI
| Molecular formula | C22H20ClN5O |
|---|---|
| Molecular weight | 405.9 g/mol |
| IUPAC name | 4-[[5-[[4-(3-chlorophenyl)-3-oxopiperazin-1-yl]methyl]imidazol-1-yl]methyl]benzonitrile |
| InChIKey | JNUGFGAVPBYSHF-UHFFFAOYSA-N |
| SMILES | C1CN(C(=O)CN1CC2=CN=CN2CC3=CC=C(C=C3)C#N)C4=CC(=CC=C4)Cl |
Computed by PubChem (NCBI)