Products 184432-08-4
CAS 184432-08-4 is the registry number for Andrastin D. Offered by: MedChemExpress. Available pack sizes: Get quote.
Andrastin D is a 3-oxo steroid that is andrastin C in which the acetoxy group at the 3beta position has undergone formal oxidative cleavage to afford the corresponding 3-oxo derivative. A farnesyltransferase inhibitor produced by Penicillium roqueforti, a filamentous fungus involved in the ripening of several kinds of blue cheeses. It has a role as an EC 2.5.1.58 (protein farnesyltransferase) inhibitor and a Penicillium metabolite. It is a 5beta steroid, a 17-oxo steroid, a methyl ester, an enol, a 15-hydroxy steroid, a 3-oxo steroid and a meroterpenoid. It is a conjugate acid of an andrastin D(1-).
Source: ChEBI
| Molecular formula | C26H36O5 |
|---|---|
| Molecular weight | 428.6 g/mol |
| IUPAC name | methyl (5S,8S,9S,10R,13R,14R)-17-hydroxy-4,4,8,10,12,13,16-heptamethyl-3,15-dioxo-1,2,5,6,7,9-hexahydrocyclopenta[a]phenanthrene-14-carboxylate |
| InChIKey | SMUNNMAWNRFDPB-UWWAQUNASA-N |
| SMILES | CC1=C[C@H]2[C@@]3(CCC(=O)C([C@H]3CC[C@@]2([C@]4([C@@]1(C(=C(C4=O)C)O)C)C(=O)OC)C)(C)C)C |
Computed by PubChem (NCBI)
Synonyms:
Andrastin D, orb2942917