Products 1859053-21-6

CAS 1859053-21-6 appears in our catalog under these names: Rucaparib Camsylate, Rucaparib monocamsylate/ 99.8% (existing batch purity), Rucaparib Camsylate, Rucaparib monocamsylate 98%, 8-Fluoro-5-(4-((methylamino)methyl)phenyl)-2,3,4,6-tetrahydro-1H-azepino[5,4,3-cd]indol-1-one ((1S,4R)-7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonate, 98%, 98%. Offered by: TRC, TargetMol, GLPBio, Biosynth, Ambeed. Available pack sizes: 250mg, 5mg, 10mg, 25mg, 50mg, 100mg, 200mg, 10mM (in 1ml dmso).

Structural formula: {0} (CAS {1})

Rucaparib camsylate is a camphorsulfonate salt obtained by reaction of rucaparib with one molar equivalent of (1S,4R)-camphorsulfonic acid. It is an inhibitor of poly (ADP-ribose) polymerase and is used as monotherapy for advanced ovarian cancer and deleterious germline or somatic BRCA mutation. It has a role as an EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor. It is an azepinoindole and a camphorsulfonate salt. It contains a rucaparib(1+) and a (S)-camphorsulfonate.

Source: ChEBI

Identity
Molecular formulaC29H34FN3O5S
Molecular weight555.7 g/mol
IUPAC name[(1S,4R)-7,7-dimethyl-2-oxo-1-bicyclo[2.2.1]heptanyl]methanesulfonic acid;6-fluoro-2-[4-(methylaminomethyl)phenyl]-3,10-diazatricyclo[6.4.1.04,13]trideca-1,4,6,8(13)-tetraen-9-one
InChIKeyINBJJAFXHQQSRW-STOWLHSFSA-N
SMILESCC1([C@@H]2CC[C@]1(C(=O)C2)CS(=O)(=O)O)C.CNCC1=CC=C(C=C1)C2=C3CCNC(=O)C4=C3C(=CC(=C4)F)N2

Computed by PubChem (NCBI)