Products 193275-84-2

CAS 193275-84-2 appears in our catalog under these names: Lonafarnib, Lonafarnib, >95% (HPLC), Lonafarnib/ 99.04% (existing batch purity), Lonafarnib 98%, (R)-4-(2-(4-(3,10-dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)piperidin-1-yl)-2-oxoethyl)piperidine-1-carboxamide, 98%, 98%. Offered by: Chemat Brand, TRC, GLPBio, TargetMol, Biosynth. Available pack sizes: on request, 100mg, 10mg, 25mg, 200mg, 5mg, 10mM (in 1ml dmso), 1mg.

Lonafarnib
Chemat Brand, GLPBio, Biosynth
  • size: on request, 10mg, 100mg, 200mg
  • Variants: 9
from 835.75
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Lonafarnib, >95% (HPLC)
TRC
  • size: 100mg, 10mg, 25mg
  • Variants: 3
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Lonafarnib/ 99.04% (existing batch purity)
TargetMol
  • size: 1mg, 5mg, 10mg, 25mg
  • Variants: 6
from 452.11
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Lonafarnib 98%
Ambeed
  • size: 1g, 1mg, 5mg, 10mg
  • Variants: 8
from 203.50
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(R)-4-(2-(4-(3,10-dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)piperidin-1-yl)-2-oxoethyl)piperidine-1-carboxamide, 98%, 98%
Chemat
  • size: 1mg, 5mg, 10mg, 25mg
  • Variants: 7
from 146.00
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Lonafarnib, 99.85%
MedChemExpress
  • size: 5 mg, 25 mg, 10mM/1mL, 10 mg
  • Variants: 6
from 695.86
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Lonafarnib (Standard)
MedChemExpress
  • size: 100 mg, 10 mg, 5 mg, 25 mg
  • Variants: 5
from 1847.57
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LONAFARNIB, 98%
Fluorochem
  • size: 1mg, 5mg, 10mg, 25mg
  • Variants: 7
from 247.85
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Lonafarnib-d9
Chemat Brand
  • size: on request
  • Variants: 1
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Structural formula: {0} (CAS {1})

Lonafarnib is a 4-{2-[4-(3,10-dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)piperidin-1-yl]-2-oxoethyl}piperidine-1-carboxamide that has R configuration. It is used as oral farnesyltransferase inhibitor. It has a role as an antineoplastic agent and an EC 2.5.1.58 (protein farnesyltransferase) inhibitor.

Source: ChEBI

Identity
Molecular formulaC27H31Br2ClN4O2
Molecular weight638.8 g/mol
IUPAC name4-[2-[4-[(2R)-6,15-dibromo-13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-yl]piperidin-1-yl]-2-oxoethyl]piperidine-1-carboxamide
InChIKeyDHMTURDWPRKSOA-RUZDIDTESA-N
SMILESC1CN(CCC1CC(=O)N2CCC(CC2)[C@@H]3C4=C(CCC5=C3N=CC(=C5)Br)C=C(C=C4Br)Cl)C(=O)N

Computed by PubChem (NCBI)

Synonyms: Lonafarnib, Sarasar, Sch 66336, Sch66336, Sch-66336, Zokinvy, lonafarnibum, Lonafarnib [USAN], C27H31Br2ClN4O2, Lonafarnib [USAN:INN]