CAS 19728-88-2 appears in our catalog under these names: Methiothepin maleate, 95%, Methiothepin Maleate, Methiothepin maleate, Methiothepin (maleate). Offered by: Combi-blocks, TRC, TargetMol, GLPBio, MedChemExpress. Available pack sizes: 100mg, 10mg, 25mg, 50mg, Get quote.
Methiothepin maleate is a maleate salt obtained by reaction of methiothepin with one equivalent of maleic acid. Potent 5-HT2 antagonist, also active as 5-HT1 antagonist. Differentiates 5-HT1D sub-types. Also displays affinity for rodent 5-HT5B, 5-HT5A, 5-HT7 and 5-HT6 receptors (pK1 values are 6.6, 7.0, 8.4 and 8.7 respectively). It has a role as an antipsychotic agent, a serotonergic antagonist and a dopaminergic antagonist. It contains a methiothepin(2+).
Source: ChEBI
| Molecular formula | C24H28N2O4S2 |
|---|---|
| Molecular weight | 472.6 g/mol |
| IUPAC name | (Z)-but-2-enedioic acid;1-methyl-4-(3-methylsulfanyl-5,6-dihydrobenzo[b][1]benzothiepin-5-yl)piperazine |
| InChIKey | IWDBEHWZGDSFHR-BTJKTKAUSA-N |
| SMILES | CN1CCN(CC1)C2CC3=CC=CC=C3SC4=C2C=C(C=C4)SC.C(=C\C(=O)O)\C(=O)O |
Computed by PubChem (NCBI)