Products 20229-30-5
CAS 20229-30-5 is the registry number for Methiothepin. Offered by: MedChemExpress. Available pack sizes: Get quote.
Methiothepin is a dibenzothiepine that is 10,11-dihydrodibenzo[b,f]thiepine bearing additional methylthio and 4-methylpiperazin-1-yl substituents at positions 8 and 10 respectively. Potent 5-HT2 antagonist, also active as 5-HT1 antagonist. Differentiates 5-HT1D sub-types. Also displays affinity for rodent 5-HT5B, 5-HT5A, 5-HT7 and 5-HT6 receptors (pK1 values are 6.6, 7.0, 8.4 and 8.7 respectively). It has a role as a geroprotector, an antipsychotic agent, a serotonergic antagonist and a dopaminergic antagonist. It is an aryl sulfide, a dibenzothiepine, a N-alkylpiperazine and a tertiary amino compound. It is a conjugate base of a methiothepin(2+).
Source: ChEBI
| Molecular formula | C20H24N2S2 |
|---|---|
| Molecular weight | 356.6 g/mol |
| IUPAC name | 1-methyl-4-(3-methylsulfanyl-5,6-dihydrobenzo[b][1]benzothiepin-5-yl)piperazine |
| InChIKey | RLJFTICUTYVZDG-UHFFFAOYSA-N |
| SMILES | CN1CCN(CC1)C2CC3=CC=CC=C3SC4=C2C=C(C=C4)SC |
Computed by PubChem (NCBI)