CAS 205254-94-0 appears in our catalog under these names: PDGFR Tyrosine Kinase Inhibitor III, PDGFR Tyrosine Kinase Inhibitor III/ 99.64% (existing batch purity), 4-(6,7-Dimethoxyquinazolin-4-yl)-N-(4-phenoxyphenyl)piperazine-1-carboxamide, 98%, 98%, PDGFR Tyrosine Kinase Inhibitor III, 99.07%, PDGFR Tyrosine Kinase Inhibitor III, 98%. Offered by: GLPBio, TargetMol, Chemat, MedChemExpress, Ambeed. Available pack sizes: 25mg, 5mg, 1mg, 10mg, 50mg, 100mg, 500mg, 50 mg.
PDGF receptor tyrosine kinase inhibitor III is an N-arylpiperazine that is piperazine in which the hydrogen attached to the nitrogen at position 1 is replaced by a (4-phenoxyphenyl)aminocarbonyl group, while the hydrogen attached to the nitrogen at position 4 is replaced by a 6,7-dimethoxyquinazolin-4-yl group. It is an inhibitor of tyrosine kinases FLT3, PDGFR and KIT. It has a role as an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor. It is a member of phenylureas, an aromatic ether, a member of quinazolines, a N-arylpiperazine, a N-carbamoylpiperazine and a tertiary amino compound.
Source: ChEBI
| Molecular formula | C27H27N5O4 |
|---|---|
| Molecular weight | 485.5 g/mol |
| IUPAC name | 4-(6,7-dimethoxyquinazolin-4-yl)-N-(4-phenoxyphenyl)piperazine-1-carboxamide |
| InChIKey | INTPTKHSGKBHHW-UHFFFAOYSA-N |
| SMILES | COC1=C(C=C2C(=C1)C(=NC=N2)N3CCN(CC3)C(=O)NC4=CC=C(C=C4)OC5=CC=CC=C5)OC |
Computed by PubChem (NCBI)