Products 206361-99-1

CAS 206361-99-1 appears in our catalog under these names: Darunavir, Darunavir, >95% (HPLC), Darunavir/ 99.69% (existing batch purity), Darunavir, 98.00%, Darunavir 98%. Offered by: Chemat Brand, TRC, Dr. Ehrenstorfer, TargetMol, GLPBio. Available pack sizes: on request, 10mg, 50mg, 5mg, 25mg, 100mg, 500mg, 10mM (in 1ml dmso).

Darunavir
Chemat Brand, Dr. Ehrenstorfer, GLPBio
  • size: on request, 50mg, 10mg, 25mg
  • Variants: 13
from 545.55
View product
Darunavir, >95% (HPLC)
TRC
  • size: 10mg, 50mg, 5mg
  • Variants: 3
View product
Darunavir/ 99.69% (existing batch purity)
TargetMol
  • size: 5mg, 10mg, 25mg, 50mg
  • Variants: 6
from 392.86
View product
Darunavir, 98.00%
Chemat
  • size: 10mg, 50mg
  • Variants: 2
from 401.34
View product
Darunavir 98%
Ambeed
  • size: 1mg, 5mg, 100mg, 250mg
  • Variants: 7
from 131.19
View product
(3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl N-[(1S,2R)-3-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]carbamate, 98%, 98%
Chemat
  • size: 250mg, 1g, 5g, 25g
  • Variants: 6
from 126.80
View product
Darunavir, 99.91%
MedChemExpress
  • size: 100 mg, 5 mg, 50 mg, 1 g
  • Variants: 8
from 310.40
View product
Darunavir (Standard)
MedChemExpress
  • size: 50 mg, 10 mg, 25 mg, 5 mg
  • Variants: 5
from 505.45
View product
Darunavir, 98%
Fluorochem
  • size: 250mg, 1g, 5g, 25g
  • Variants: 4
from 232.23
View product
Structural formula: {0} (CAS {1})

Darunavir is an N,N-disubstituted benzenesulfonamide bearing an unsubstituted amino group at the 4-position, used for the treatment of HIV infection. A second-generation HIV protease inhibitor, darunavir was designed to form robust interactions with the protease enzyme from many strains of HIV, including those from treatment-experienced patients with multiple resistance mutations to other protease inhibitors. It has a role as a HIV protease inhibitor and an antiviral drug. It is a carbamate ester, a sulfonamide and a furofuran.

Source: ChEBI

Identity
Molecular formulaC27H37N3O7S
Molecular weight547.7 g/mol
IUPAC name[(3aS,4R,6aR)-2,3,3a,4,5,6a-hexahydrofuro[2,3-b]furan-4-yl] N-[(2S,3R)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl]carbamate
InChIKeyCJBJHOAVZSMMDJ-HEXNFIEUSA-N
SMILESCC(C)CN(C[C@H]([C@H](CC1=CC=CC=C1)NC(=O)O[C@H]2CO[C@@H]3[C@H]2CCO3)O)S(=O)(=O)C4=CC=C(C=C4)N

Computed by PubChem (NCBI)

Synonyms: Darunavir, Darunavirum, (-)-DARUNAVIR, Ethanolate, Darunavir, Prezista, Darunavirum [INN-Latin], Derunavir, 2ien, Darunavir [USAN:INN:BAN], 2f8g
Related forms of this compound
[(3aS,4R,6aR)-2,3,3a,4,5,6a-hexahydrofuro[2,3-b]furan-4-yl] N-[(2S,3S)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl]carbamate C27H37N3O7S
[(3aR,4S,6aS)-2,3,3a,4,5,6a-hexahydrofuro[2,3-b]furan-4-yl] N-[(2R,3S)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl]carbamate C27H37N3O7S
[(3aS,4R,6aR)-2,3,3a,4,5,6a-hexahydrofuro[2,3-b]furan-4-yl] N-[(2R,3S)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl]carbamate C27H37N3O7S
[(3aS,4R,6aR)-2,3,3a,4,5,6a-hexahydrofuro[2,3-b]furan-4-yl] N-[(2R,3R)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl]carbamate C27H37N3O7S
[(3aR,4S,6aS)-2,3,3a,4,5,6a-hexahydrofuro[2,3-b]furan-4-yl] N-[(2S,3R)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl]carbamate C27H37N3O7S
[(3aS,4R,6aR)-2,3,3a,4,5,6a-hexahydrofuro[2,3-b]furan-4-yl] N-[(2S,3R)-4-[(4-aminophenyl)sulfonyl-[1,1,2,3,3,3-hexadeuterio-2-(trideuteriomethyl)propyl]amino]-3-hydroxy-1-phenylbutan-2-yl]carbamate C27H37N3O7S