Products 206648-13-7
CAS 206648-13-7 appears in our catalog under these names: CGP 78608, CGP 78608 hydrochloride, CGP-78608. Offered by: TRC, GLPBio, Biosynth, MedChemExpress. Available pack sizes: 75mg, 10mg, 50mg, 0,05g, Get quote.
CGP 78608 is a phosphonic acid in which the hydrogen attached to phosphorous is substituted by a 1-{[(7-bromo-2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-5-yl)methyl]amino}ethyl group. Potent and selective NMDA antagonist that acts through the glycine site (IC50 = 5 nM). Displays >500-fold selectivity over kainate and AMPA receptors (IC50 values are 2.7 and 3 M respectively). Anticonvulsant in vivo following systemic administration. It has a role as an anticonvulsant and a NMDA receptor antagonist. It is a member of phosphonic acids, an organobromine compound, a quinoxaline derivative and a secondary amino compound. It contains a CGP 78608(1+).
Source: ChEBI
| Molecular formula | C11H13BrN3O5P |
|---|---|
| Molecular weight | 378.12 g/mol |
| IUPAC name | [(1S)-1-[(7-bromo-2,3-dioxo-1,4-dihydroquinoxalin-5-yl)methylamino]ethyl]phosphonic acid |
| InChIKey | DPFHVUSPVHRVFL-YFKPBYRVSA-N |
| SMILES | C[C@@H](NCC1=C2C(=CC(=C1)Br)NC(=O)C(=O)N2)P(=O)(O)O |
Computed by PubChem (NCBI)
Synonyms:
Tocris-1493, orb1739531