Products 208255-80-5

CAS 208255-80-5 appears in our catalog under these names: DAPT, >95% (HPLC), DAPT (GSI–IX), DAPT/ 99.81% (existing batch purity), DAPT , DAPT. Offered by: TRC, GLPBio, TargetMol, Thermo Scientific (Alfa Aesar), Biosynth. Available pack sizes: 10mg, 50mg, 10mM (in 1ml dmso), 500mg, 5mg, 25mg, 100mg, 200mg.

DAPT, >95% (HPLC)
TRC
  • size: 10mg, 50mg
  • Variants: 2
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DAPT (GSI–IX)
GLPBio
  • size: 10mg, 10mM (in 1ml dmso), 50mg, 500mg
  • Variants: 4
from 620.44
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DAPT/ 99.81% (existing batch purity)
TargetMol
  • size: 5mg, 10mg, 25mg, 50mg
  • Variants: 7
from 532.05
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DAPT
Thermo Scientific (Alfa Aesar), Biosynth, Sigma-Aldrich
  • size: 10mg, 50mg, 25MG, 5MG
  • Variants: 5
from 1184.57
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(3,5-Difluorophenylacetyl)-Ala-Phg-OtBu
Biosynth
  • size: 5mg, 10mg
  • Variants: 2
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DAPT [Optimized for Cell Culture]
TCI
  • size: 5mg
  • Variants: 1
from 934.61
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DAPT, >97.0%(HPLC)
TCI
  • size: 25mg
  • Variants: 1
from 836.26
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DAPT, 98.00%
Chemat
  • size: 25mg, 5mg
  • Variants: 2
from 691.83
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DAPT 98%
Ambeed
  • size: 5g, 1mg, 5mg, 10mg
  • Variants: 9
from 136.75
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╬│-Secretase Inhibitor IX 1PC X 10MG
Sigma-Aldrich
  • size: 10MG
  • Variants: 1
from 973.00
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╬│-Secretase Inhibitor IX 1PC X 1GM
Sigma-Aldrich
  • size: 1GM
  • Variants: 1
from 81160.00
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╬│-Secretase Inhibitor IX 1PC X 200MG
Sigma-Aldrich
  • size: 200MG
  • Variants: 1
from 34300.00
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╬│-Secretase Inhibitor IX 1PC X 250MG
Sigma-Aldrich
  • size: 250MG
  • Variants: 1
from 81160.00
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╬│-Secretase Inhibitor IX 1PC X 500MG
Sigma-Aldrich
  • size: 500MG
  • Variants: 1
from 81160.00
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╬│-Secretase Inhibitor IX 1PC X 575MG
Sigma-Aldrich
  • size: 575MG
  • Variants: 1
from 81160.00
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╬│-Secretase Inhibitor IX 1PC X 5MG
Sigma-Aldrich
  • size: 5MG
  • Variants: 1
from 733.00
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tert-Butyl (S)-2-((S)-2-(2-(3,5-difluorophenyl)acetamido)propanamido)-2-phenylacetate, 98%, 98%
Chemat
  • size: 1mg, 5mg, 10mg, 25mg
  • Variants: 8
from 122.00
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DAPT, 99.97%
MedChemExpress
  • size: 5 mg, 50 mg, 25 mg, 200 mg
  • Variants: 7
from 440.44
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DAPT (GMP), 99.3%
MedChemExpress
  • size: 50 mg, 10 mg
  • Variants: 2
from 6259.37
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Structural formula: {0} (CAS {1})

DAPT is a dipeptide consisting of alanylphenylglycine derivatised as a 3,5-difluorophenylacetamide at the amino terminal and a tert-butyl ester at the carboxy terminal. It is a gamma-secretase inhibitor. It has a role as an EC 3.4.23.46 (memapsin 2) inhibitor. It is a tert-butyl ester, a carboxylic ester, a difluorobenzene and a dipeptide.

Source: ChEBI

Identity
Molecular formulaC23H26F2N2O4
Molecular weight432.5 g/mol
IUPAC nametert-butyl (2S)-2-[[(2S)-2-[[2-(3,5-difluorophenyl)acetyl]amino]propanoyl]amino]-2-phenylacetate
InChIKeyDWJXYEABWRJFSP-XOBRGWDASA-N
SMILESC[C@@H](C(=O)N[C@@H](C1=CC=CC=C1)C(=O)OC(C)(C)C)NC(=O)CC2=CC(=CC(=C2)F)F

Computed by PubChem (NCBI)

Synonyms: dapt, GSI-IX, DAPT (GSI-IX), gamma-Secretase Inhibitor IX, GSI IX, DAPT (GMP), one of |A-Secretase inhibitor, tert-butyl (2S)-({N-[(3,5-difluorophenyl)acetyl]-L-alanyl}amino)(phenyl)acetate, DAPT (peptide), (3,5-Difluorophenylacetyl)-Ala-Phg-OtBu