Products 210751-39-6

CAS 210751-39-6 is the registry number for LY 367265. Offered by: MedChemExpress. Available pack sizes: Get quote.

Structural formula: {0} (CAS {1})

LY-367,265 is a fluoroindole that is 1H-indole in which the hydrogens at positions 3 and 6 are replaced by 1-[2-(2,2-dioxo-5,6-dihydro-4H-26-[1,2,5]thiadiazolo[4,3,2-ij]quinolin-1(2H)-yl)ethyl]-1,2,3,6-tetrahydropyridin-4-yl and fluoro groups, respectively. It is an inhibitor of the 5-hydroxytryptamine transporter (Ki = 2.3 nM) and an antagonist of 5-hydroxytryptamine(2A) receptor (Ki = 0.81 nM). It has a role as a geroprotector, an antidepressant, a serotonergic antagonist and a serotonin uptake inhibitor. It is a fluoroindole, a thiadiazoloquinoline, a dihydropyridine and a tertiary amino compound.

Source: ChEBI

Identity
Molecular formulaC24H25FN4O2S
Molecular weight452.5 g/mol
IUPAC name3-[2-[4-(6-fluoro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]-2lambda6-thia-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-triene 2,2-dioxide
InChIKeyBJIPVHLRWSDKOS-UHFFFAOYSA-N
SMILESC1CC2=C3C(=CC=C2)N(S(=O)(=O)N3C1)CCN4CCC(=CC4)C5=CNC6=C5C=CC(=C6)F

Computed by PubChem (NCBI)