CAS 219580-11-7 appears in our catalog under these names: PD 173074, PD-173074, PD173074/ 98.21% (existing batch purity), PD 173074, PD 173074, >95.0%(HPLC). Offered by: Chemat Brand, TRC, TargetMol, GLPBio, TCI. Available pack sizes: on request, 10mg, 1mg, 5mg, 25mg, 50mg, 100mg, 200mg.
PD173074 is a member of the class of ureas that is 1-tert-butylurea in which one of the hydrogens attached to N3 is substituted by a pyrido[2,3-d]pyrimidin-7-yl group, which is itself substituted at positions 2 and 6 by a 4-(diethylamino)butyl]amino group and a 3,5-dimethoxyphenyl group, respectively. It is a FGF/VEGF receptor tyrosine kinase inhibitor. It has a role as an antineoplastic agent, an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor and a fibroblast growth factor receptor antagonist. It is an aromatic amine, a pyridopyrimidine, a member of ureas, a tertiary amino compound, a dimethoxybenzene and a biaryl. It is functionally related to a PD-166866.
Source: ChEBI
| Molecular formula | C28H41N7O3 |
|---|---|
| Molecular weight | 523.7 g/mol |
| IUPAC name | 1-tert-butyl-3-[2-[4-(diethylamino)butylamino]-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]urea |
| InChIKey | DXCUKNQANPLTEJ-UHFFFAOYSA-N |
| SMILES | CCN(CC)CCCCNC1=NC2=NC(=C(C=C2C=N1)C3=CC(=CC(=C3)OC)OC)NC(=O)NC(C)(C)C |
Computed by PubChem (NCBI)