Products 219769-23-0

CAS 219769-23-0 is the registry number for SB-284851-BT. Offered by: MedChemExpress. Available pack sizes: Get quote.

Structural formula: {0} (CAS {1})

SB-284851-BT is a piperidinylimidazole that is 1H-imidazole carrying a piperidin-4-yl group, 4-fluorophenyl group and a 2-(3,5-dimethylphenoxy)pyrimidin-4-yl group at positions 1, 4 and 5 respectively. It is a potent inhibitor of p38alpha mitogen-activated protein kinase and BRD4. It has a role as a bromodomain-containing protein 4 inhibitor and an EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor. It is an aryloxypyrimidine, a piperidinylimidazole and a member of monofluorobenzenes.

Source: ChEBI

Identity
Molecular formulaC26H26FN5O
Molecular weight443.5 g/mol
IUPAC name2-(3,5-dimethylphenoxy)-4-[5-(4-fluorophenyl)-3-piperidin-4-ylimidazol-4-yl]pyrimidine
InChIKeyUVLWMBRFRAMDOW-UHFFFAOYSA-N
SMILESCC1=CC(=CC(=C1)OC2=NC=CC(=N2)C3=C(N=CN3C4CCNCC4)C5=CC=C(C=C5)F)C

Computed by PubChem (NCBI)

Synonyms: orb1739665