Products 2226735-55-1

CAS 2226735-55-1 appears in our catalog under these names: (S)-6-(4-(5-(3,5-Difluorophenyl)-4,5-dihydro-1H-pyrazole-1-carbonyl)piperidin-1-yl)pyrimidine-4-carbonitrile, 99+%, GSK547, GSK547 , GSK'547, GSK547, 99.92%. Offered by: BLDpharm, Chemat, TargetMol, GLPBio, Biosynth. Available pack sizes: 25mg, 50mg, 100mg, 250mg, 1mg, 5mg, 10mg, 2mg.

(S)-6-(4-(5-(3,5-Difluorophenyl)-4,5-dihydro-1H-pyrazole-1-carbonyl)piperidin-1-yl)pyrimidine-4-carbonitrile, 99+%
BLDpharm, Chemat
  • size: 25mg, 50mg, 100mg, 250mg
  • Variants: 10
from 203.60
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GSK547
TargetMol, GLPBio
  • size: 2mg, 5mg, 10mg, 25mg
  • Variants: 12
from 419.13
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GSK'547
Biosynth
  • size: 25mg, 50mg, 100mg
  • Variants: 3
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GSK547, 99.92%
MedChemExpress
  • size: 10 mg, 50 mg, 10mM/1mL, 100 mg
  • Variants: 7
from 695.86
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GSK547, 99+%
Ambeed
  • size: 100mg, 250mg
  • Variants: 2
from 2984.75
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Structural formula: {0} (CAS {1})

GSK547 (GSK'547) is a highly selective and potent inhibitor of receptor-interacting serine/threonine protein kinase 1 (RIPK1), inhibits macrophage-mediated adaptive immune tolerance in pancreatic cancer.

Source: ChEBI

Identity
Molecular formulaC20H18F2N6O
Molecular weight396.4 g/mol
IUPAC name6-[4-[(3S)-3-(3,5-difluorophenyl)-3,4-dihydropyrazole-2-carbonyl]piperidin-1-yl]pyrimidine-4-carbonitrile
InChIKeySJVGFKBLUYAEOK-SFHVURJKSA-N
SMILESC1CN(CCC1C(=O)N2[C@@H](CC=N2)C3=CC(=CC(=C3)F)F)C4=NC=NC(=C4)C#N

Computed by PubChem (NCBI)

Synonyms: orb1225622, orb1299856, example 6 [WO2020044206A1]