CAS 23583-48-4 appears in our catalog under these names: 8-Bromoadenosine 3',5'-cyclic monophosph, ate, 250 mg, 8-Br-camp, 95%, 8-bromo-Cyclic AMP, 8–bromo–Cyclic AMP, 8-Bromoadenosine-3',5'-cyclic . Offered by: Roth, Combi-blocks, TargetMol, GLPBio, Thermo Scientific (Alfa Aesar). Available pack sizes: 250mg, 100mg, 10mg, 25mg, 50mg, 5mg, 500mg, 2000mg.
8-Br-cAMP is a 3',5'-cyclic purine nucleotide that is 3',5'-cyclic AMP bearing an additional bromo substituent at position 8 on the adenine ring. An activator of cyclic AMP-dependent protein kinase, but resistant to degradation by cyclic AMP phosphodiesterase. It has a role as an antidepressant and a protein kinase agonist. It is a 3',5'-cyclic purine nucleotide, an organobromine compound and an adenyl ribonucleotide. It is functionally related to a 3',5'-cyclic AMP.
Source: ChEBI
| Molecular formula | C10H11BrN5O6P |
|---|---|
| Molecular weight | 408.10 g/mol |
| IUPAC name | (4aR,6R,7R,7aS)-6-(6-amino-8-bromopurin-9-yl)-2-hydroxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol |
| InChIKey | DVKQVRZMKBDMDH-UUOKFMHZSA-N |
| SMILES | C1[C@@H]2[C@H]([C@H]([C@@H](O2)N3C4=NC=NC(=C4N=C3Br)N)O)OP(=O)(O1)O |
Computed by PubChem (NCBI)